875781-45-6

• 常用中文名：2-溴-7-碘-5-甲苯磺酰基-5H-吡咯并[2,3-B]吡嗪
• 常用英文名：2-Bromo-7-iodo-5-tosyl-5H-pyrrolo[2,3-b]pyrazine
• CAS号：875781-45-6
• 分子式：C₁₃H₉BrIN₃O₂S
• 分子量：478.103
• 发布时间：2018-10-09 20:03:36
• 更新时间：2024-01-06 10:42:53

名称

• 中文名: 2-溴-7-碘-5-甲苯磺酰基-5H-吡咯并[2,3-B]吡嗪
• 英文名: 2-Bromo-7-iodo-5-tosyl-5H-pyrrolo[2,3-b]pyrazine
• 英文别名: 2-Bromo-7-iodo-5-[(4-methylphenyl)sulfonyl]-5H-pyrrolo[2,3-b]pyrazine; 2-bromo-7-iodo-5-(4-methylphenyl)sulfonylpyrrolo[2,3-b]pyrazine; 5H-Pyrrolo[2,3-b]pyrazine, 2-bromo-7-iodo-5-[(4-methylphenyl)sulfonyl]-

物化性质

• 密度: 2.1±0.1 g/cm3
• 沸点: 560.1±60.0 °C at 760 mmHg
• 分子式: C₁₃H₉BrIN₃O₂S
• 分子量: 478.103
• 闪点: 292.6±32.9 °C
• 精确质量: 476.864349
• PSA: 73.23000
• LogP: 3.69
• 蒸汽压: 0.0±1.5 mmHg at 25°C
• 折射率: 1.777

合成路线

875781-44-5 98-59-9 ~92% 875781-45-6

文献：UNIVERSITY OF ROCHESTER; BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA; GELBARD, Harris A.; DEWHURST, Stephen; GENDELMAN, Howard E. Patent: WO2014/85795 A1, 2014 ; Location in patent: Paragraph 0284 ;

875781-43-4 98-59-9 ~99% 875781-45-6

文献：SGX PHARMACEUTICALS, INC. Patent: WO2006/15124 A2, 2006 ; Location in patent: Page/Page column 103 ; WO 2006/015124 A2

875781-41-2 ~% 875781-45-6

文献：UNIVERSITY OF ROCHESTER; GELBARD, Harris, A.; DEWHURST, Stephen; GOODFELLOW, Val, S.; WIEMANN, Torsten; RAVULA, Satheesh, Babu; LOWETH, Colin, J. Patent: WO2011/149950 A2, 2011 ; WO 2011/149950 A2

875781-42-3 ~% 875781-45-6

文献：UNIVERSITY OF ROCHESTER; GELBARD, Harris, A.; DEWHURST, Stephen; GOODFELLOW, Val, S.; WIEMANN, Torsten; RAVULA, Satheesh, Babu; LOWETH, Colin, J. Patent: WO2011/149950 A2, 2011 ; WO 2011/149950 A2

875781-43-4 ~% 875781-45-6

文献：UNIVERSITY OF ROCHESTER; GELBARD, Harris, A.; DEWHURST, Stephen; GOODFELLOW, Val, S.; WIEMANN, Torsten; RAVULA, Satheesh, Babu; LOWETH, Colin, J. Patent: WO2011/149950 A2, 2011 ; WO 2011/149950 A2