16088-19-0

• 常用中文名：N,N-二甲基氨基甲酸3-(二甲基氨基)苯酯
• 常用英文名：Nor Neostigmine
• CAS号：16088-19-0
• 分子式：C₁₁H₁₆N₂O₂
• 分子量：208.25700
• 发布时间：2018-11-28 15:21:30
• 更新时间：2026-09-22 15:31:54

名称

• 中文名: N,N-二甲基氨基甲酸3-(二甲基氨基)苯酯
• 英文名: Nor Neostigmine
• 中文别名: NOR新斯的明; 新斯的明杂质C; 新斯的明杂质C(NOR新斯的明); 3-(二甲氨基)苯基二甲基氨基甲酸酯 (新斯的明杂质); 非新斯的明; 新斯的明杂质3(新斯的明杂质C)(非新斯的明); 3-(二甲氨基)苯基二甲基氨基甲酯; 甲硫酸新斯的明杂质C; 溴新斯的明杂质C; 溴新斯的明杂质A; 异新斯的明; N-去甲新斯的明; N,N-二甲基氨基甲酸-3-(二甲基氨基)苯酯; N,N-二甲基氨基甲酸间(二甲基氨基)苯酯; 3-二甲基氨基苯基-氨基甲酸二甲酯; 去甲新斯的明; 3-(二甲基氨基)苯基 二甲基氨基甲酸酯; 溴化新斯的明杂质C; 新斯的明杂质C(非新斯的明); 3-(二甲氨基)苯基 N,N-二甲基氨基甲酸酯; 降新斯的明; 甲硫酸新斯的明中间体2
• 英文别名: Neostigmine bromide Impurity C; Neostigmine methylsulfate Intermediate 2; Einecs -5; Neostigmine Impurity C (Nor; Neostigmine Impurity C (Nor Neostigmine); Dimethylcbamic acid m-(dimethylamino)phenyl ester; Neostigmine Impurity C; 3-(Dimethylamino)phenyl dimethylcbamate (Neostigmine Impurity); DiMethylcbaMic Acid 3-(DiMethylaMino)phenyl Ester; 3-(Dimethylamino)phenyl N,N-dimethylcbamate; [3-(dimethylamino)phenyl] N,N-dimethylcarbamate; Cbamic acid, N,N-dimethyl-, 3-(dimethylamino)phenyl ester; norneostigmine; N,N-Dimethylcbamic acid 3-(dimethylamino)phenyl ester; Neostigmine Impurity 3(Neostigmine Impurity C)(Nor Neostigmine); 3-Dimethylaminophenyl-N,N-Dimethylaminocbonate; m-(Dimethylamino)phenyl N,N-dimethyl-cbamate; 3-dimethylaminophenyl dimethylcbamate

物化性质

• 密度: 1.102g/cm3
• 沸点: 313.6ºC at 760mmHg
• 分子式: C₁₁H₁₆N₂O₂
• 分子量: 208.25700
• 闪点: 143.5ºC
• 精确质量: 208.12100
• PSA: 32.78000
• LogP: 1.81300
• 蒸汽压: 0.00049mmHg at 25°C
• 折射率: 1.551

安全

• 海关编码: 2924299090

合成路线

7244-70-4 99-07-0 ~93% 16088-19-0

文献：NEON LABORATORIES LTD.; DALVI, Mahesh Bhagoji; KENNY, Rajesh Shashikant; TARADE, Pradeep Kisan; CHINCHKAR, Dattatray Krishna Patent: WO2012/131699 A1, 2012 ; Location in patent: Page/Page column 14 ;

99-07-0 79-44-7 ~% 16088-19-0

文献：Barbarini, Jose E.; Rittner, Roberto; Hoeehr, Nelci F.; Suwinski, Jerzy Bioorganic Chemistry, 1997 , vol. 25, # 1 p. 37 - 41

79-44-7 ~% 16088-19-0

文献：Bobranskii; Eker Zhurnal Prikladnoi Khimii (Sankt-Peterburg, Russian Federation), 1941 , vol. 14, p. 524,526 Chem.Abstr., 1942 , p. 3159

52177-71-6 124-40-3 ~% 16088-19-0

文献：Hoffmann-La Roche Patent: DE535835 , 1928 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 17, p. 2567

114-80-7 ~% 19962-04-0 16088-19-0 76418-45-6 详细

文献：Porst; Kny Pharmazie, 1985 , vol. 40, # 5 p. 325 - 328

75-44-5 124-40-3 99-07-0 ~% 16088-19-0

文献：Ward Jr.; Freeman; Sowell; Kosh Journal of Pharmaceutical Sciences, 1981 , vol. 70, # 4 p. 433 - 435

74-83-9 591-27-5 79-44-7 ~% 19962-04-0 详细

文献：Porst; Kny Pharmazie, 1985 , vol. 40, # 5 p. 325 - 328

海关

海关编码	2924299090
中文概述	2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 包装
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%