61263-35-2

• 常用中文名：甲烯前列素
• 常用英文名：meteneprost
• CAS号：61263-35-2
• 分子式：C₂₃H₃₈O₄
• 分子量：378.545
• 相关类别： 原料药 激素及调节内分泌功能类药 前列腺素类药
• 发布时间：2018-05-25 08:00:00
• 更新时间：2026-07-29 14:17:31

名称

• 中文名: 甲烯前列素
• 英文名: Meteneprost
• 中文别名: 化合物:9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2; 化合物：9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2; 9-脱氧-9-亚甲基-16,16-二甲基前列腺素E2
• 英文别名: metenrostum; 7-(5,5-dimethyl-3-hydroxy-2-(3-hydroxy-1-octenyl)cyclopentyl)-5-htenoicaci; 9-deoxo-16,16-dimethyl-9-methylenrostaglandine2; 9-Deoxo-16,16-dimethyl-9-methylenrostaglandine E2; Prosta-5,13-dien-1-oic acid, 11,15-dihydroxy-16,16-dimethyl-9-methylene-, (5Z,11α,13E,15R); 9-DEOXY-9-METHYLENE-16,16-DIMETHYL PROSTAGLANDIN E2; METENPROST; 9-deoxo-16,16-dimethyl-9-methylene-pge2; 5-htenoicacid,7-(5,5-dimethyl-3-hydroxy-2-(3-hydroxy-1-octenyl)cyclopentyl); 9-Deoxy-16,16-diMethyl-9-Methylene-PGF2; (5Z,11α,13E,15S)-16,16-Dimethyl-9-methylene-11,15-dihydroxyprosta-5,13-dien-1-oic acid; metenrost; (5Z,11α,13E,15R)-11,15-Dihydroxy-16,16-dimethyl-9-methyleneprosta-5,13-dien-1-oic acid; 9-DEOXY-9-METHYLENE-16,16-DIMETHYL PROSTAGLANDIN E2 //BP; 9-METHYLENE-11ALPHA,15R-DIHYDROXY-16,16-DIMETHYL-PROSTA-5Z,13E-DIEN-1-OIC ACID; (5Z,11α,13E,15R)-11,15-Dihydroxy-16,16-diMethyl-9-Methylenrosta-5,13-dien-1-oic Acid; (5Z,11α,13E,15S)-16,16-Dimethyl-9-methylene-11,15-dihydroxyprosta-5,13-diene-1-oic acid; (5Z,11α,13E,15R)-11,15-dihydroxy-16,16-dimethyl-9-methylideneprosta-5,13-dien-1-oic acid; (Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3R)-3-hydroxy-4,4-dimethyloct-1-enyl]-5-methylidenecyclopentyl]hept-5-enoic acid; 9-Deoxo-9-Methylene-16,16-diMethyl-PGE2; (5Z,11a,13E,15R)-11,15-dihydroxy-16,16-dimethyl-9-methyleneprosta-5,13-dien-1-oic Acid; (5Z,11α,13E,15S)-11,15-Dihydroxy-16,16-dimethyl-9-methylenrosta-5,13-dien-1-oic acid

物化性质

• 密度: 1.0±0.1 g/cm3
• 沸点: 520.5±50.0 °C at 760 mmHg
• 分子式: C₂₃H₃₈O₄
• 分子量: 378.545
• 闪点: 282.7±26.6 °C
• 精确质量: 378.277008
• PSA: 77.76000
• LogP: 4.54
• 蒸汽压: 0.0±3.1 mmHg at 25°C
• 折射率: 1.524

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : MJ9671600 CHEMICAL NAME : 5-Heptenoic acid, 7-(5,5-dimethyl-3-hydroxy-2-(3-hydroxy-1-octenyl)cycl opentyl)- CAS REGISTRY NUMBER : 61263-35-2 LAST UPDATED : 199706 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C23-H38-O4 MOLECULAR WEIGHT : 378.61 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intravenous DOSE : 60 ug/kg SEX/DURATION : female 16 week(s) after conception TOXIC EFFECTS : Reproductive - Maternal Effects - uterus, cervix, vagina REFERENCE : CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 22,153,1980 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intravaginal DOSE : 3 mg/kg SEX/DURATION : female 16 week(s) after conception TOXIC EFFECTS : Reproductive - Maternal Effects - uterus, cervix, vagina REFERENCE : CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 22,153,1980 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intravaginal DOSE : 800 ug/kg SEX/DURATION : female 13 week(s) after conception TOXIC EFFECTS : Reproductive - Fertility - abortion REFERENCE : CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 22,153,1980