36950-85-3

• 常用中文名：20-乙基前列腺素F2α
• 常用英文名：20-ethyl prostaglandin f2alpha
• CAS号：36950-85-3
• 分子式：C₂₂H₃₈O₅
• 分子量：382.534
• 发布时间：2016-03-30 10:40:15
• 更新时间：2024-04-03 22:35:17

名称

• 中文名: 20-乙基前列腺素F2α
• 英文名: 20-ethyl prostaglandin f2alpha
• 英文别名: (5Z)-7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-1-decen-1-yl]cyclopentyl}-5-heptenoic acid; (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxydec-1-en-1-yl]cyclopentyl}hept-5-enoic acid (non-preferred name); 9alpha,11alpha,15s-trihydroxy-20a,20b-dihomoprosta-5z,13e-dien-1-oic acid

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 551.7±50.0 °C at 760 mmHg
• 分子式: C₂₂H₃₈O₅
• 分子量: 382.534
• 闪点: 301.5±26.6 °C
• 精确质量: 382.271912
• PSA: 97.99000
• LogP: 3.21
• 蒸汽压: 0.0±3.4 mmHg at 25°C
• 折射率: 1.560

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : MJ9653000 CHEMICAL NAME : 5-Heptenoic acid, 7-(3,5-dihydroxy-2-(3-hydroxy-1-decenyl)cyclopentyl)- , (1R-(1-alpha(Z),2-beta(1E,3S*),3-alpha,5-alpha))- CAS REGISTRY NUMBER : 36950-85-3 LAST UPDATED : 198910 DATA ITEMS CITED : 7 MOLECULAR FORMULA : C22-H38-O5 MOLECULAR WEIGHT : 382.60 WISWESSER LINE NOTATION : L5TJ AQ B6VQ C1U1YQ7 DQ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 4 mg/kg SEX/DURATION : female 4-7 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) REFERENCE : PRGLBA Prostaglandins. (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022) V.1- 1972- Volume(issue)/page/year: 2,375,1972 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 40 mg/kg SEX/DURATION : female 19-20 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - abortion REFERENCE : PRGLBA Prostaglandins. (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022) V.1- 1972- Volume(issue)/page/year: 2,375,1972 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 10 mg/kg SEX/DURATION : female 4-7 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - other measures of fertility REFERENCE : PRGLBA Prostaglandins. (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022) V.1- 1972- Volume(issue)/page/year: 2,375,1972 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 2250 ug/kg SEX/DURATION : female 4-6 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - other measures of fertility REFERENCE : NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736) V.1- 1869- Volume(issue)/page/year: 238,400,1972 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 100 ug/kg SEX/DURATION : female 4-6 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - other measures of fertility REFERENCE : NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736) V.1- 1869- Volume(issue)/page/year: 238,400,1972 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 150 ug/kg SEX/DURATION : female 4-6 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) REFERENCE : NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736) V.1- 1869- Volume(issue)/page/year: 238,400,1972 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 2500 ug/kg SEX/DURATION : female 14 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - abortion REFERENCE : PRGLBA Prostaglandins. (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022) V.1- 1972- Volume(issue)/page/year: 2,375,1972