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1596-70-9生产厂家

1596-70-9价格

1596-70-9

1596-70-9结构式
1596-70-9结构式

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英文名 levopropoxyphene hydrochloride
英文别名 D-propoxyphene
2-Butanol,4-(dimethylamino)-3-methyl-1,2-diphenyl-,propionate (ester),hydrochloride,(L)
(2R,3S)-4-Dimethylamino-3-methyl-1,2-diphenyl-2-propionyloxy-butan,Hydrochlorid
L-Propoxyphene hydrochloride
(2R,3S)-4-dimethylamino-3-methyl-1,2-diphenyl-2-propionyloxy-butane,hydrochloride
Levopropoxyphene HCl
[4-(dimethylamino)-3-methyl-1,2-diphenylbutan-2-yl] propanoate,hydrochloride
Levopropoxyphene hydrochloride
[4-(dimethylamino)-3-methyl-1,2-diphenylbutan-2-yl] propanoate hydrochloride
沸点 444ºC at 760mmHg
分子式 C22H30ClNO2
分子量 375.93200
闪点 130.6ºC
精确质量 375.19700
PSA 29.54000
LogP 5.07750
蒸汽压 4.43E-08mmHg at 25°C
储存条件 -20°C,密闭,干燥

CHEMICAL IDENTIFICATION

RTECS NUMBER :
EL3050000
CHEMICAL NAME :
2-Butanol, 4-(dimethylamino)-3-methyl-1,2-diphenyl-, propionate (ester), hydrochloride, (L)-
CAS REGISTRY NUMBER :
1596-70-9
LAST UPDATED :
199012
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C22-H29-N-O2.Cl-H
MOLECULAR WEIGHT :
375.98
WISWESSER LINE NOTATION :
2VOXR&1R&Y1&1N1&1 &GH -L

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
182 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RPOBAR Research Progress in Organic-Biological and Medicinal Chemistry. (New York, NY) V.1-3, 1964-72. Discontinued. Volume(issue)/page/year: 2,320,1970
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
114 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - other changes
REFERENCE :
JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 63,451,1974
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
20 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RPOBAR Research Progress in Organic-Biological and Medicinal Chemistry. (New York, NY) V.1-3, 1964-72. Discontinued. Volume(issue)/page/year: 2,319,1970