24639-06-3

• 常用中文名：2-氯-2',3'-O-异丙亚基腺苷
• 常用英文名：Adenosine,2-chloro-2',3'-O-(1-methylethylidene)- (9CI)
• CAS号：24639-06-3
• 分子式：C₁₃H₁₆ClN₅O₄
• 分子量：341.75000
• 发布时间：2016-06-22 05:54:19
• 更新时间：2026-08-15 10:03:51

名称

• 中文名: 2-氯-2',3'-O-异丙亚基腺苷
• 英文名: 2-Chloroadenosine-2,,3,-acetonide
• 中文别名: ((3,4R,6R,6-6-(6-氨基-2-氯-9H-嘌呤-9-基)-2,2-二甲基四氢呋喃并[3,4-D][1,3]二氧杂环戊烯-4-基)甲醇
• 英文别名: 2-Chloro-2',3'-O-isopropylideneadenosine; ((3,4R,6R,6-6-(6-amino-2-chloro-9H-purin-9-yl)-2,2-diMethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)Methanol; 2-CHLORO-9-(2,3-O-ISOPROPYLIDENE-β-D-RIBOFURANOSYL)ADENINE; 2-Chloroadenosine-2′,3′-acetonide; (3,4R,6R,6-6-(6-amino-2-chloro-9H-purin-9-yl)-2,2-dimethyl-tetrahydro-2H-furo[3,4-d][1,3]dioxol-4-yl]methanol; ((3,4R,6R,6-6-(6-Amino-2-chloro-9H-purin-9-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]diox; 2-chloro-9-(2,3-o-isopropylidene-β-d-ribofuranosyl)adenine; [(3,4R,6R,6-4-(6-amino-2-chloropurin-9-yl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]methanol; 2-CHLORO-9-(2,3-O-ISOPROPYLIDENE-BETA-D-RIBOFURANOSYL)ADENINE; 2-Chloro-2',3'-O-isopropylidene-D-adenosine; Adenosine, 2-chloro-2',3'-O-(1-methylethylidene); 2-Chloro-2',3'-O-(1-Methylethylidene)adenosine

物化性质

• 密度: 1.9g/cm3
• 沸点: 517.7ºC at 760mmHg
• 分子式: C₁₃H₁₆ClN₅O₄
• 分子量: 341.75000
• 闪点: 266.9ºC
• 精确质量: 341.08900
• PSA: 117.54000
• LogP: 1.05290
• 蒸汽压: 1.52E-11mmHg at 25°C
• 折射率: 1.806
• 储存条件: 2-8°C，避光，保存于惰性气体中

合成路线

146-77-0 77-76-9 ~99% 24639-06-3

文献：Borcherding, David R.; Lentz, Nelsen L.; Weintraub, Philip M.; Dudley, Mark W.; Secrest, Roberta; Kastner, Philip R.; Peet, Norton P. Nucleosides and Nucleotides, 1999 , vol. 18, # 10 p. 2175 - 2191

146-77-0 77-76-9 67-64-1 ~71% 24639-06-3

文献：GENZYME CORPORATION Patent: WO2008/157438 A1, 2008 ; Location in patent: Page/Page column 13; 22 ;

1078724-45-4 77-76-9 ~% 24639-06-3

文献：Cellzome AG; Harrison, John; Addison, Glynn; Ramsden, Nigel; Drewes, Gerard Patent: US2013/210664 A1, 2013 ; Location in patent: Paragraph 0176; 0177 ;

146-77-0 67-64-1 ~% 24639-06-3

文献：CAMBRIDGE BIOTECHNOLOGY LIMITED Patent: WO2005/84653 A2, 2005 ; Location in patent: Page/Page column 50 ; WO 2005/084653 A2

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