21232-47-3

• 常用中文名：双(3,4-二氯苯基)二氮烯-1-氧化物
• 常用英文名：3,3',4,4'-TETRACHLOROAZOXYBENZENE
• CAS号：21232-47-3
• 分子式：C₁₂H₆Cl₄N₂O
• 分子量：336.00100
• 发布时间：2018-10-14 16:11:37
• 更新时间：2024-01-14 22:36:19

名称

• 中文名: 双(3,4-二氯苯基)二氮烯-1-氧化物
• 英文名: (3,4-dichlorophenyl)-(3,4-dichlorophenyl)imino-oxidoazanium
• 中文别名: 3,3',4,4'-四氯偶氮氧苯
• 英文别名: Diazene,bis(3,4-dichlorophenyl)-,1-oxide; 3,3',4,4'-tetrachloroazoxybenzole; TCAOB; bis-(3,4-dichloro-phenyl)-diazene-N-oxide; Azoxybenzene,3,3',4,4'-tetrachloro; 3,3',4,4'-Tetrachlor-azoxybenzol; 3,3',4,4'-TETRACHLOROAZOXYBENZENE; Bis-(3,4-dichlor-phenyl)-diazen-N-oxid; Bis(3,4-dichlorophenyl)diazene 1-oxide; 3,4,3',4'-Tetrachloroazoxybenzene; 3,4,3',4'-Tetrachlor-azoxybenzol

物化性质

• 密度: 1.53g/cm3
• 沸点: 472.7ºC at 760 mmHg
• 分子式: C₁₂H₆Cl₄N₂O
• 分子量: 336.00100
• 闪点: 239.7ºC
• 精确质量: 333.92300
• PSA: 41.11000
• LogP: 6.74910
• 蒸汽压: 1.19E-08mmHg at 25°C
• 折射率: 1.641

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : CO4150000 CHEMICAL NAME : Azoxybenzene, 3,3',4,4'-tetrachloro- CAS REGISTRY NUMBER : 21232-47-3 LAST UPDATED : 199712 DATA ITEMS CITED : 11 MOLECULAR FORMULA : C12-H6-Cl4-N2-O MOLECULAR WEIGHT : 336.00 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 80 mg/kg/17W-C TOXIC EFFECTS : Liver - changes in liver weight Blood - changes in erythrocyte (RBC) count Related to Chronic Data - changes in testicular weight TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 650 mg/kg/13W-I TOXIC EFFECTS : Behavioral - food intake (animal) Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 350 mg/kg/48D-I TOXIC EFFECTS : Liver - other changes Endocrine - changes in thymus weight Related to Chronic Data - changes in testicular weight TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 200 mg/kg/28D-I TOXIC EFFECTS : Liver - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 75600 ug/kg SEX/DURATION : female 14 day(s) pre-mating - 28 day(s) post-birth TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - blood and lymphatic systems (including spleen and marrow) Reproductive - Effects on Newborn - live birth index (measured after birth) TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 7560 ug/kg SEX/DURATION : female 14 day(s) pre-mating - 28 day(s) post-birth TOXIC EFFECTS : Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain) TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intraperitoneal DOSE : 16 mg/kg SEX/DURATION : female 12 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetal death TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intraperitoneal DOSE : 6 mg/kg SEX/DURATION : female 11 day(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - urogenital system MUTATION DATA TEST SYSTEM : Rodent - mouse DOSE/DURATION : 134 mg/kg/4W (Continuous) REFERENCE : AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- Volume(issue)/page/year: 14,677,1985

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