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4075-43-8


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英文名 Rifamycin, 8-(morpholinomethyl)
英文别名 PF-49
NCI 144-143
2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-1,11(2H)-dione,5,6,9,17,19,21-hexahydroxy-2,4,12,16,18,20,22-heptamethyl-23-methoxy-8-(morpholinomethyl)-,21-acetate
密度 1.35g/cm3
沸点 907.6ºC at 760 mmHg
分子式 C42H56N2O13
分子量 796.90000
闪点 502.7ºC
精确质量 796.37800
PSA 213.78000
LogP 4.66220
折射率 1.634

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KD1920700
CHEMICAL NAME :
2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b) furan-1,11(2H)-dione, 5,6,9,17,19,21- hexahydroxy-2,4,12,16,18,20,22-heptamethyl-23-methoxy -8-(morpholinomethyl) -, 21-acetate
CAS REGISTRY NUMBER :
4075-43-8
LAST UPDATED :
199712
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C42-H56-N2-O13
MOLECULAR WEIGHT :
797.00

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
188 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
38KLAC "Structure-Activity Relationship among the Semisynthetic Antibiotics," Perlman, D., ed., New York, Academic Press, 1977 Volume(issue)/page/year: -,531,1977

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