139481-58-6

• 常用中文名：坎地沙坦乙酯
• 常用英文名：Candesartan ethyl ester
• CAS号：139481-58-6
• 分子式：C₂₆H₂₄N₆O₃
• 分子量：468.507
• 相关类别： 原料药 循环系统用药 抗高血压病药
• 发布时间：2018-08-20 21:31:49
• 更新时间：2026-07-15 21:41:55

名称

• 中文名: 乙基 -2-乙氧基-1-[[(2'-(1H四zol-5-基)联苯-4-基-) 甲基]
• 英文名: ethyl 2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylate
• 中文别名: 坎地沙坦中间体 C7; 坎地沙坦CILEXETIL 杂质A; 坎地沙坦乙酯杂质Ⅰ; 2-乙氧基-1-[[(2'-(1H-四唑-5-基)联苯-4-基)甲基]苯并咪唑]-7-甲酸乙酯; 坎地沙坦酯杂质; 坎地沙坦乙酯-A); 坎地氢噻杂质1; 坎地沙坦西酯相关化合物A; 坎地沙坦 西里西替林 杂质A; 坎地沙坦西酯 杂质A; 坎地沙坦酯中间体(乙酯C7); 坎地沙坦酯杂质1(坎地沙坦酯杂质A); 坎地沙坦酯中间体乙酯C7; 坎地沙坦酯杂质A(坎地沙坦乙酯); 坎地沙坦杂质 6; 坎地沙坦酯杂质A; 坎地沙坦酯杂质Ⅰ; 坎地沙坦酯乙酯
• 英文别名: 2-Ethoxy-l- [[2'-(2H-Tetrazol-5-YI)[l,l,-Biphenyl]-4-YI] Methyl]-1H- Benzimidazole-7-Cboxylic Acid Ethyl Ester; Candestan Cilexetil Impurity A/Candestan Ethyl Ester Candestan Impurity A; T56 BN DNJ CO2 IVO2 B1R DR B- ET5MNNNJ; Ethyl 1-((2-(2H-tetrazol-5-yl)-[1,1-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-cboxylate; Candestan Cilexetil Impurity 1(Candestan Cilexetil Impurity A); 1H-BenziMidazole-7-cboxylic acid, 2-ethoxy-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]Methyl]-, ethyl ester; Candestan Cilexetil Impurity Ⅰ; Candesartan Ethyl Ester; Ethyl 2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-carboxylate; Candestan Cilexetil Impurity A (Candestan Ethyl Ester); Candestan Cilexetil Imp. A : Ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-cboxylate; 2-Ethoxy-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-cboxylic acid ethyl ester; Candestan ester; Ethyl -2-ethoxy-1-[[(2-(1Htetrazol-5-yl)biphenyl-4-yl-) methyl],Candestan Ethyl Ester; 1H-BenziMidazole-7-cboxylicacid,2-ethoxy-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]Methyl]-,ethylesteror2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]Methyl]-,1H-benziMidazole-7-cboxylicethylester; Ethyl 1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-c; Ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylate; Candestan Imp A; Candestan Cilexetil IMpurity A; Candestan Impurity A; Ethyl 2-ethoxy-1-{[2'-(2H-tetrazol-5-yl)-4-biphenylyl]methyl}-1H-benzimidazole-7-carboxylate; (Ethyl 1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-2-ethoxybenzimidazole-7-cboxylate); candestan cilexetil impurity1362; ethyl 1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-cboxylate; Ethyl 2-ethoxy-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylate; Ethyl 2-Ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]-1H-benzimidazole-7-cboxylate; CandestanEthylEste; Ethyl -2-ethoxy-1-[[(2-(1Htetrazol-5-yl)biphenyl-4-yl-) meth; Candestan Impurity 6; Candestan Ethyl Ester //BP; Ethyl -2-ethoxy-1-[[(2-(1Htetrazol-5-yl)biphenyl-4-yl-) methyl]; 1H-Benzimidazole-7-carboxylic acid, 2-ethoxy-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, ethyl ester; Candestan Ethyl Ester; Candestan Cilexetil Impurity AQ: What is Candestan Cilexetil Impurity A Q: What is the CAS Number of Candestan Cilexetil Impurity A Q: What is the storage condition of Candestan Cilexetil Impurity A Q: What e the applications of Candestan Cilexetil Impurity A; Candestan Cilexetil Impurity 1 Impurity A); Candestan Cilexetil Related Compound A; Candestan Impurity A Candestan Ethyl Ester; Candesartan Cilexetil Impurity 1; Ethyl -2-ethoxy-1-[[(2-(1Htetrazol-5-yl)biphenyl-4-yl-) methyl] //BP; Ethyl Candestan; 2-Ethoxy-1-[[2-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-cboxylic Acid ethyl ester; Candestan Impurity -A; UNII-8TT2Y1F36J

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 709.6±70.0 °C at 760 mmHg
• 熔点: 157-159ºC
• 分子式: C₂₆H₂₄N₆O₃
• 分子量: 468.507
• 闪点: 382.9±35.7 °C
• 精确质量: 468.190979
• PSA: 107.81000
• LogP: 5.85
• 外观性状: 粉末
• 蒸汽压: 0.0±2.3 mmHg at 25°C
• 折射率: 1.677
• 储存条件: Refrigerator

安全

• 危险品运输编码: NONH for all modes of transport

合成路线

139481-41-7 ~% 139481-58-6

文献：WO2008/44244 A2, ; Page/Page column 5 ;

854538-88-8 155884-01-8 ~40% 139481-58-6

文献：QUIMICA SINTETICA, S.A. Patent: WO2006/134078 A1, 2006 ; Location in patent: Page/Page column 16 ;

916891-91-3 ~58% 139481-58-6

文献：QUIMICA SINTETICA, S.A. Patent: WO2006/134078 A1, 2006 ; Location in patent: Page/Page column 20 ;

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139481-41-7 854538-88-8 155884-01-8
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139481-59-7