119170-52-4

• 常用中文名：决明子苷C
• 常用英文名：Cassiaside C
• CAS号：119170-52-4
• 分子式：C₂₇H₃₂O₁₅
• 分子量：596.53400
• 相关类别： 研究领域 代谢疾病
• 发布时间：2018-06-20 22:29:39
• 更新时间：2026-08-06 13:59:58
• Cassiaside C (Toralactone 9-O-β-D-gentiobioside) 是从决明子种子中分离得到的一种萘酚类化合物,对晚期糖基化终产物 (AGE) 的形成具有抑制作用。

名称

• 中文名: 决明子苷C
• 英文名: Toralactone 9-O-beta-D-gentiobioside
• 中文别名: 决明内酯-龙胆双糖苷; Cassiaside C #天然产物 HY-N7628
• 英文别名: 9-[(6-O-β-D-Glucopyranosyl-β-D-glucopyranosyl)oxy]-10-hydroxy-3-methyl-1H-naphtho[2,3-c]pyran-1-one //BP; cassiaside C; Rivoxaban Impurity 18 Hydrochloride; toralactone-9-O-gentiobioside; 1H-Naphtho[2,3-c]pyran-1-one, 9-[(6-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-10-hydroxy-7-methoxy-3-methyl; 9-[(6-O-β-D-Glucopyranosyl-β-D-glucopyranosyl)oxy]-10-hydroxy-3-methyl-1H-naphtho[2,3-c]pyran-1-one; 10-Hydroxy-7-methoxy-3-methyl-9-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxymethyl)-tetrahydro-pyran-2-yloxy]-benzo[g]isochromen-1-one; toralactone 9-O-yl β-D-glucopyranosyl-(1->6)-β-D-glucopyranoside; 1H-Naphtho[2,3-c]pyran-1-one,9-[(6-O-b-D-glucopyranosyl-b-D-glucopyranosyl)oxy]-10-hydroxy-7-methoxy-3-methyl; nhropathy,Diabetic,mesangial cell,end products,Endogenous Metabolite,Cassiae Semen,TGF-β1,Cassiaside C,Advanced glycation,Inhibitor,inhibit; toralactone-9-O-β-D-gentiobioside

物化性质

• 分子式: C₂₇H₃₂O₁₅
• 分子量: 596.53400
• 精确质量: 596.17400
• PSA: 238.20000
• 储存条件: 2-8℃

生物活性

• 描述: Cassiaside C (Toralactone 9-O-β-D-gentiobioside) 是从决明子种子中分离得到的一种萘酚类化合物,对晚期糖基化终产物 (AGE) 的形成具有抑制作用。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 代谢疾病
• 靶点:

  IC50: AGE formation[1]

• 参考文献:

  [1]. Yu-Lin Diao, et al. A new comprehensive procedure for the quality control of Semen Cassiae and its application in evaluating commercially available material in China. Chin J Nat Med. 2013 Jul;11(4):433-41.

  [2]. Dong Ho Jung, et al. Extract of Cassiae Semen and its major compound inhibit S100b-induced TGF-beta1 and fibronectin expression in mouse glomerular mesangial cells. Eur J Pharmacol. 2010 Sep 1;641(1):7-14.