219923-05-4

• 常用中文名：N-[(5S)-6,7-二氢-9,10,11-三甲氧基-3-(磷酰氧基)-5H-二苯并[A,C]环庚烯-5-基]乙酰胺
• 常用英文名：ZD6126
• CAS号：219923-05-4
• 分子式：C₂₀H₂₄NO₈P
• 分子量：437.380
• 发布时间：2017-06-07 23:08:35
• 更新时间：2026-07-01 14:58:30

名称

• 中文名: N-[(5S)-6,7-二氢-9,10,11-三甲氧基-3-(磷酰氧基)-5H-二苯并[A,C]环庚烯-5-基]乙酰胺
• 英文名: (5S)-5-Acetamido-9,10,11-trimethoxy-6,7-dihydro-5H-dibenzo[a,c][7 ]annulen-3-yl dihydrogen phosphate
• 英文别名: N-Acetylcolchicinol dihydrogenphosphate; AZD6126, ANG453; Acetamide, N-[(5S)-6,7-dihydro-9,10,11-trimethoxy-3-(phosphonooxy)-5H-dibenzo[a,c]cyclohten-5-yl]; N-acetylcolchinol-O-phosphate; phosphoric acid mono-((S)-5-acetylamino-9,10,11-trimethoxy-6,7-dihydro-5H-dibenzo[a,c]cyclohepten-3-yl) ester; ANG 453; AZD6126; (5S)-5-Acetamido-9,10,11-trimethoxy-6,7-dihydro-5H-dibenzo[a,c][7]annulen-3-yl dihydrogen phosphate; ZD-6126; N-acetylcochinol-O-phosphate; (5S)-5-(acetylamino)-9,10,11-trimethoxy-6,7-dihydro-5H-dibenzo[a,c][7]annulen-3-yl dihydrogen phosphate; N-[(5S)-6,7-Dihydro-9,10,11-trimethoxy-3-(phosphonooxy)-5H-dibenzo[a,c]cyclohten-5-yl]acetamide

物化性质

• 密度: 1.4±0.1 g/cm3
• 分子式: C₂₀H₂₄NO₈P
• 分子量: 437.380
• 精确质量: 437.123962
• PSA: 136.85000
• LogP: 1.55
• 折射率: 1.608

合成路线

701232-77-1 ~78% 219923-05-4

文献：AVENTIS PHARMA S.A. Patent: US2004/138182 A1, 2004 ; Location in patent: Page 5 ;

38838-26-5 ~% 219923-05-4

文献：Broady, Simon D.; Golden, Michael D.; Leonard, John; Muir, James C.; Maudet, Mickael Tetrahedron Letters, 2007 , vol. 48, # 26 p. 4627 - 4630

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