143268-82-0

• 常用中文名：8-fluoro-6-hydroxy-3,4-dihydro-1H-quinolin-2-one
• 常用英文名：8-fluoro-6-hydroxy-3,4-dihydro-1H-quinolin-2-one
• CAS号：143268-82-0
• 分子式：C₉H₈FNO₂
• 分子量：181.16400
• 发布时间：2016-09-14 18:05:10
• 更新时间：2025-09-10 21:04:04

名称

• 英文名: 8-fluoro-6-hydroxy-3,4-dihydro-1H-quinolin-2-one

物化性质

• 分子式: C₉H₈FNO₂
• 分子量: 181.16400
• 精确质量: 181.05400
• PSA: 52.82000
• LogP: 1.50110

合成路线

143268-81-9 ~62% 143268-82-0

文献：Fujioka; Teramoto; Mori; Hosokawa; Sumida; Tominaga; Yabuuchi Journal of Medicinal Chemistry, 1992 , vol. 35, # 20 p. 3607 - 3612

1371589-26-2 ~% 143268-82-0

文献：N30 PHARMACEUTICALS, LLC; SUN, Xicheng; QIU, Jian; STOUT, Adam Patent: WO2012/48181 A1, 2012 ; Location in patent: Page/Page column 79-80 ; WO 2012/048181 A1

399-95-1 ~% 143268-82-0

文献：N30 PHARMACEUTICALS, LLC; SUN, Xicheng; QIU, Jian; STOUT, Adam Patent: WO2012/48181 A1, 2012 ; WO 2012/048181 A1

143268-79-5 ~% 143268-82-0

文献：BRISTOL-MYERS SQUIBB COMPANY; King, Dalton; Macor, John E.; Olson, Richard E.; Iwuagwu, Christiana I.; Karageorge, George N. Patent: US2013/79338 A1, 2013 ; US 20130079338 A1

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