144485-86-9

• 常用中文名：6-methyl-3-(3-methyl-1,2-oxazol-5-yl)quinazolin-4-one
• 常用英文名：6-methyl-3-(3-methyl-1,2-oxazol-5-yl)quinazolin-4-one
• CAS号：144485-86-9
• 分子式：C₁₃H₁₁N₃O₂
• 分子量：241.24500
• 发布时间：2016-05-05 18:40:17
• 更新时间：2024-01-15 22:58:23

名称

• 英文名: 6-methyl-3-(3-methyl-1,2-oxazol-5-yl)quinazolin-4-one

物化性质

• 密度: 1.35g/cm3
• 沸点: 471.4ºC at 760 mmHg
• 分子式: C₁₃H₁₁N₃O₂
• 分子量: 241.24500
• 闪点: 238.9ºC
• 精确质量: 241.08500
• PSA: 60.92000
• LogP: 1.99050
• 蒸汽压: 4.66E-09mmHg at 25°C
• 折射率: 1.67

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : VA3679020 CHEMICAL NAME : 4(3H)-Quinazolinone, 6-methyl-3-(3-methyl-5-isoxazolyl)- CAS REGISTRY NUMBER : 144485-86-9 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C13-H11-N3-O2 MOLECULAR WEIGHT : 241.27 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1 gm/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - ptosis Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression REFERENCE : FRMCE8 Farmaco. (Societa Chimica Italiana, Corso Strada Nova, 86, Casella Postale 227, 27100 Pavia, Italy) V.44- 1989- Volume(issue)/page/year: 47,465,1992 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 500 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - ptosis Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression REFERENCE : FRMCE8 Farmaco. (Societa Chimica Italiana, Corso Strada Nova, 86, Casella Postale 227, 27100 Pavia, Italy) V.44- 1989- Volume(issue)/page/year: 47,465,1992

合成路线

38818-49-4 ~% 144485-86-9

文献：Plescia; Diadone; Raffa; Bajardi; Caruso; Cutuli; Amico-Roxas Farmaco, 1992 , vol. 47, # 4 p. 465 - 475

144486-01-1 ~% 144485-86-9

文献：Plescia; Diadone; Raffa; Bajardi; Caruso; Cutuli; Amico-Roxas Farmaco, 1992 , vol. 47, # 4 p. 465 - 475

上下游产品

上游产品  2
38818-49-4 144486-01-1
下游产品  0