89151-46-2

• 常用中文名：4-(2-碘乙基)哌啶-1-羧酸叔丁酯
• 常用英文名：1-Boc-4-(2-iodoethyl)piperidine
• CAS号：89151-46-2
• 分子式：C₁₂H₂₂INO₂
• 分子量：339.21300
• 发布时间：2018-12-01 18:37:12
• 更新时间：2024-02-03 18:16:21

名称

• 中文名: 4-(2-碘乙基)-1-哌啶羧酸叔丁酯
• 英文名: tert-butyl 4-(2-iodoethyl)piperidine-1-carboxylate
• 英文别名: 1-BOC-4-(2-IODOETHYL)PIPERIDINE; 2-(N-t-Butyloxycarbonylpiperidin-4-yl)ethyl iodide; 4-(2-iodoethyl)piperidine-1-carbamic acid tert-butyl ester; 1-Piperidinecarboxylic acid,4-(2-iodoethyl)-,1,1-dimethylethyl ester; 4-(2-iodoeth-1-yl)-1-tert-butoxycarbonylpiperidine; t-butyl 4-(2-iodoethyl)-1-piperidinecarboxylate; 1-tert-butyloxycarbonyl-4-(2-iodo-ethyl)-piperidine; 4-(2-iodo-1-ethyl)-1-tert-butoxycarbonyl-piperidine

物化性质

• 密度: 1.406±0.06 g/cm3(Predicted)
• 沸点: 351.9±15.0 °C(Predicted)
• 分子式: C₁₂H₂₂INO₂
• 分子量: 339.21300
• 精确质量: 339.07000
• PSA: 29.54000
• LogP: 3.39650
• 储存条件: 2-8°C

合成路线

89151-44-0 ~10% 89151-46-2

文献：Villalobos; Blake; Biggers; Butler; Chapin; Chen; Ives; Jones; Liston; Nagel; Nason; Nielsen; Shalaby; White Journal of Medicinal Chemistry, 1994 , vol. 37, # 17 p. 2721 - 2734

288-32-4 89151-44-0 ~59% 89151-46-2

文献：Merck and Co., Inc. Patent: US5321034 A1, 1994 ;

89151-44-0 98-59-9 ~% 89151-46-2

文献：Pfizer Inc. Patent: US4489075 A1, 1984 ;

622-26-4 ~% 89151-46-2

文献：Lynch, Christopher L.; Willoughby, Christopher A.; Hale, Jeffrey J.; Holson, Edward J.; Budhu, Richard J.; Gentry, Amy L.; Rosauer, Keith G.; Caldwell, Charles G.; Chen, Ping; Mills, Sander G.; MacCoss, Malcolm; Berk, Scott; Chen, Liya; Chapman, Kevin T.; Malkowitz, Lorraine; Springer, Martin S.; Gould, Sandra L.; DeMartino, Julie A.; Siciliano, Salvatore J.; Cascieri, Margaret A.; Carella, Anthony; Carver, Gwen; Holmes, Karen; Schleif, William A.; Danzeisen, Renee; Hazuda, Daria; Kessler, Joseph; Lineberger, Janet; Miller, Michael; Emini, Emilio A. Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 1 p. 119 - 123

24424-99-5 ~% 89151-46-2

文献：Lynch, Christopher L.; Willoughby, Christopher A.; Hale, Jeffrey J.; Holson, Edward J.; Budhu, Richard J.; Gentry, Amy L.; Rosauer, Keith G.; Caldwell, Charles G.; Chen, Ping; Mills, Sander G.; MacCoss, Malcolm; Berk, Scott; Chen, Liya; Chapman, Kevin T.; Malkowitz, Lorraine; Springer, Martin S.; Gould, Sandra L.; DeMartino, Julie A.; Siciliano, Salvatore J.; Cascieri, Margaret A.; Carella, Anthony; Carver, Gwen; Holmes, Karen; Schleif, William A.; Danzeisen, Renee; Hazuda, Daria; Kessler, Joseph; Lineberger, Janet; Miller, Michael; Emini, Emilio A. Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 1 p. 119 - 123

上下游产品

上游产品  5
89151-44-0 288-32-4 98-59-9 622-26-4
24424-99-5
下游产品  2
347873-67-0 146093-46-1