97281-47-5

• 常用中文名：葵花磷脂
• 常用英文名：lecithin
• CAS号：97281-47-5
• 分子式：C₄₂H₈₀NO₈P
• 分子量：758.060
• 相关类别： 生物化工 脂肪类药
• 发布时间：2018-04-06 16:49:16
• 更新时间：2026-07-01 21:27:59
• Phosphatidylcholines,soya 是一种从大豆中提取的磷脂酰胆碱,可用于脂质体的制备。Phosphatidylcholines,soya 可作为动物给药的载体。

名称

• 中文名: 卵磷脂
• 英文名: 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine
• 中文别名: 大豆 PC; 人二倍体细胞; L-Α-磷脂酰胆碱(大豆); SPC响应型磷脂; 磷脂酰胆碱(大豆); 向日葵卵磷脂; 卵磷脂(大豆) 医药级-可用作注射; Phosphatidylcholines,soya (Synonyms: 大豆磷脂酰胆碱); L-Α-磷脂酰胆碱 (大豆-); 卵磷酯(大豆)
• 英文别名: L-ALPHA-LECITHIN TYPE XVI-E; L-ALPHA-LECITHIN TYPE IV-S; L-ALPHA-PHOSPHATIDYLCHOLINES, PC (SOYBEAN); L-ALPHA-PHOSPHATIDYLCHOLINES, PC (SOYBEAN, HYDROGENATED); Sunflower lecithin; LECITHINS; L-ALPHA-LECITHIN TYPE III-B; 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE TYPE X-E; 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE TYPE I-EH; LECITHIN MIXTURES VI; LECITHOL; VITELLIN; L-α-phosphatidylcholine (Soy); PHOSPHATIDYLCHOLINE; BRAIN PC; LECITHIN MIXTURES IV; LECITHIN MIXTURES V; L-ALPHA-LECITHIN TYPE XI-E; EINECS 306-547-4; LECITHIN MIXTURES III; 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE TYPE III-B; SOYABEANPHOSPHATIDYLCHOLINE; EGG LECITHIN; L-ALPHA-LECITHIN TYPE X-E; 3-sn-Phosphatidylcholine (soya); PHOSPHATIDYCHOLINE; PC, SOYBEAN; Phosphatidylcholines, soya; L-ALPHA-LECITHIN TYPE XIII-E; 3-SN-PHOSPHATIDYLCHOLINE; AZOLECTIN; 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE TYPE III-S; L-ALPHA-LECITHIN TYPE III-S; L-ALPHA-LECITHIN TYPE II-S; 1-PALMITOYL-2-DOCOSAHEXAENOYL-SN-GLYCERO-3-[PHOSPHO-L-SERINE](SODIUM SALT); L-Α-PHOSPHATIDYLCHOLINE (SOY);SOY PC; (2R)-2-[(9Z,12Z)-9,12-Octadecadienoyloxy]-3-(palmitoyloxy)propyl 2-(trimethylammonio)ethyl phosphate; SOYBEANPHOSPHATIDYLCHOLINE; OVOLECITHIN; COATSOME NC-20 (SPC); 16::6 PS (SODIUM SALT); EGG PC; 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE TYPE II-S; SOY PC; LECITHIN(Egg)(RG); HYDRO PC; 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE TYPE XI-E; 1,2-DIACTYL-SN-GLYCERO-3-PHOSPHOCHOLINE TYPE XVI-E; LECITHIN MIXTURES VII; LIVER PC; LECITHIN MIXTURES VIII; EGG YOLK LECITHIN; 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE TYPE IV-S; Ethanaminium, 2-[[hydroxy[(2R)-3-[(1-oxohexadecyl)oxy]-2-[[(9Z,12Z)-1-oxo-9,12-octadecadien-1-yl]oxy]propoxy]phosphinyl]oxy]-N,N,N-trimethyl-, inner salt; HET PC; [(2R)-3-hexadecanoyloxy-2-[(9Z,12Z)-octadeca-9,12-dienoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate; L-ALPHA-LECITHIN, EGG YOLK; LECITHIN SOYA BEAN; 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE TYPE XIII-E; L-ALPHA-LECITHIN TYPE I-EH

物化性质

• 分子式: C₄₂H₈₀NO₈P
• 分子量: 758.060
• 精确质量: 757.562134
• LogP: 10.90
• 外观性状: 黄色至棕色粘性液体或糊状物、粉末或颗粒
• 储存条件: −20°C
• 计算化学:

  1.疏水参数计算参考值（XlogP）:12.9

  2.氢键供体数量:0

  3.氢键受体数量:8

  4.可旋转化学键数量:40

  5.互变异构体数量:无

  6.拓扑分子极性表面积111

  7.重原子数量:52

  8.表面电荷:0

  9.复杂度:941

  10.同位素原子数量:0

  11.确定原子立构中心数量:1

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:2

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

生物活性

• 描述: Phosphatidylcholines,soya 是一种从大豆中提取的磷脂酰胆碱,可用于脂质体的制备。Phosphatidylcholines,soya 可作为动物给药的载体。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 其他 >> 其他
• 体外研究: 成纤维细胞对IC50为150μM的大豆磷脂酰胆碱脂质体具有敏感性[3]。
• 参考文献:

  [1]. Thomas AH, et al. Soybean phosphatidylcholine liposomes as model membranes to study lipid peroxidation photoinduced by pterin. Biochim Biophys Acta. 2016 Jan;1858(1):139-45.

  [2]. Formariz TP, et al. Doxorubicin biocompatible O/W microemulsion stabilized by mixed surfactant containing soya phosphatidylcholine. Colloids Surf B Biointerfaces. 2006 Aug 1;51(1):54-61.

  [3]. Berrocal MC, et al. Comparison of the effects of dimyristoyl and soya phosphatidylcholine liposomes on human fibroblasts. Drug Deliv. 2000 Jan-Mar;7(1):37-44.

安全

• 危险品运输编码: NONH for all modes of transport
• WGK德国: 1
• RTECS号: OG7565000
• 闪点（华氏）: >199.4 °F
• 闪点（摄氏）: >93 °C