725474-97-5

• 常用中文名：GIP(1-39)
• 常用英文名：GIP(1-39)
• CAS号：725474-97-5
• 分子式：C₂₁₀H₃₁₆N₅₆O₆₁S
• 分子量：
• 相关类别： 研究领域 代谢疾病
• 发布时间：2018-07-17 02:45:10
• 更新时间：2024-01-26 23:18:26
• GIP (1-39) (Gastric inhibitory peptide (1-39) (porcine)) 是一种促胰岛素肽,可刺激大鼠胰岛分泌胰岛素。100 nM 的 GIP(1-39) 能显著增加胞内 Ca2+ 浓度([Ca2+]i),并能增强胞外分泌。

名称

• 英文名: (4S)-5-[[2-[[(1S,2R)-1-[[(1S)-2-[[(1S,2S)-1-[[(1S)-2-[[(1S)-2-[[(1S)-2-[[(1S)-2-[[(1S,2S)-1-[[(1S)-2-[[(1S)-1-[[(1S)-2-[[(1S)-5-amino-1-[[(1S,2S)-1-[[(1S)-1-[[(1S)-4-amino-1-[[(1S)-4-amino-1-[[(1S)-2-[[(1S)-2-[[(1S)-1-[[(1S)-3-amino-1-[[(1S)-2-[[(1S)-1-[[(1S)-1-[[(1S)-2-[[(1S)-4-amino-1-[[(1S)-5-amino-1-[[2-[[(1S)-5-amino-1-[[(1S)-5-amino-1-[[(1S)-2-[[(1S)-2-[[(1S)-2-[[(1S)-5-amino-1-[[(1S)-2-[[(1S)-3-amino-1-carboxy-3-oxo-propyl]amino]-1-(1H-imidazol-4-ylmethyl)-2-oxo-ethyl]carbamoyl]pentyl]amino]-1-(1H-indol-3-ylmethyl)-2-oxo-ethyl]amino]-1-(carboxymethyl)-2-oxo-ethyl]amino]-1-(hydroxymethyl)-2-oxo-ethyl]carbamoyl]pentyl]carbamoyl]pentyl]amino]-2-oxo-ethyl]carbamoyl]pentyl]carbamoyl]-4-oxo-butyl]amino]-1-methyl-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]carbamoyl]-3-methyl-butyl]amino]-1-(1H-indol-3-ylmethyl)-2-oxo-ethyl]carbamoyl]-3-oxo-propyl]carbamoyl]-2-methyl-propyl]amino]-1-benzyl-2-oxo-ethyl]amino]-1-(carboxymethyl)-2-oxo-ethyl]carbamoyl]-4-oxo-butyl]carbamoyl]-4-oxo-butyl]carbamoyl]-4-guanidino-butyl]carbamoyl]-2-methyl-butyl]carbamoyl]pentyl]amino]-1-(carboxymethyl)-2-oxo-ethyl]carbamoyl]-3-methylsulfanyl-propyl]amino]-1-methyl-2-oxo-ethyl]carbamoyl]-2-methyl-butyl]amino]-1-(hydroxymethyl)-2-oxo-ethyl]amino]-1-[(4-hydroxyphenyl)methyl]-2-oxo-ethyl]amino]-1-(carboxymethyl)-2-oxo-ethyl]amino]-1-(hydroxymethyl)-2-oxo-ethyl]carbamoyl]-2-methyl-butyl]amino]-1-benzyl-2-oxo-ethyl]carbamoyl]-2-hydroxy-propyl]amino]-2-oxo-ethyl]amino]-4-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-5-oxo-pentanoic acid

物化性质

• 分子式: C₂₁₀H₃₁₆N₅₆O₆₁S

生物活性

• 描述: GIP (1-39) (Gastric inhibitory peptide (1-39) (porcine)) 是一种促胰岛素肽,可刺激大鼠胰岛分泌胰岛素。100 nM 的 GIP(1-39) 能显著增加胞内 Ca2+ 浓度([Ca2+]i),并能增强胞外分泌。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 代谢疾病
• 参考文献:

  [1]. Xie L, et al. GIP1-39, a novel insulinotropic peptide form and aspects on its mechanism of action. Regul Pept. 2004 Sep 15;121(1-3):107-12.