425629-94-3

• 常用中文名：PfDHODH-IN-2
• 常用英文名：PfDHODH-IN-2
• CAS号：425629-94-3
• 分子式：C₁₃H₁₂ClNO₃S
• 分子量：297.757
• 发布时间：2021-01-09 09:11:42
• 更新时间：2024-01-04 12:29:03
• PfDHODH-IN-2, a dihydrothiophenone derivative (Compound 11), is a potent Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) inhibitor with an IC50 of 1.11 µM. PfDHODH-IN-2 acts as an antimalarial agent and can be used for the research of malaria.

名称

• 英文名: PfDHODH-IN-2
• 英文别名: Ethyl 2-[(4-chlorophenyl)amino]-4-oxo-4,5-dihydro-3-thiophenecarboxylate; 3-Thiophenecarboxylic acid, 2-[(4-chlorophenyl)amino]-4,5-dihydro-4-oxo-, ethyl ester

物化性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 427.5±45.0 °C at 760 mmHg
• 分子式: C₁₃H₁₂ClNO₃S
• 分子量: 297.757
• 闪点: 212.3±28.7 °C
• 精确质量: 297.022644
• LogP: 2.77
• 蒸汽压: 0.0±1.0 mmHg at 25°C
• 折射率: 1.664