57385-16-7

• 常用中文名：4-乙炔-四氢-2H-吡喃-4-醇
• 常用英文名：2H-Pyran-4-ol, 4-ethynyltetrahydro- (9CI)
• CAS号：57385-16-7
• 分子式：C₇H₁₀O₂
• 分子量：126.15300
• 发布时间：2019-02-16 10:23:43
• 更新时间：2024-01-06 11:07:00

名称

• 中文名: 4-乙炔-四氢-2H-吡喃-4-醇
• 英文名: 4-ethynyloxan-4-ol
• 英文别名: 4-ethynyltetrahydro-2H-pyran-4-ol; 4-ethynyl-tetrahydro-pyran-4-ol; 2H-Pyran-4-ol,4-ethynyltetrahydro

物化性质

• 分子式: C₇H₁₀O₂
• 分子量: 126.15300
• 精确质量: 126.06800
• PSA: 29.46000
• LogP: 0.16110

合成路线

542-28-9 4301-14-8 ~96% 57385-16-7

文献：F. HOFFMANN-LA ROCHE AG Patent: WO2004/52869 A1, 2004 ; Location in patent: Page 151 - 152 ; WO 2004/052869 A1

1044277-44-2 ~% 57385-16-7

文献：Grimm, Erich L.; Ducharme, Yves; Frenette, Richard; Friesen, Richard; Gagnon, Marc; Juteau, Helene; Laliberte, Sebastien; MacKay, Bruce; Gareau, Yves Patent: US2008/188521 A1, 2008 ; Location in patent: Page/Page column 24 ;

29943-42-8 65032-27-1 ~% 57385-16-7

文献：VITAE PHARMACEUTICALS, INC.; CLAREMON, David A.; LEFTHERIS, Katerina; SINGH, Suresh B.; TICE, Colin M.; YE, Yuanjie; ZHUANG, Linghang; ZHAO, Wei Patent: WO2011/2910 A1, 2011 ; Location in patent: Page/Page column 79 ; WO 2011/002910 A1

29943-42-8 4301-14-8 ~78% 57385-16-7

文献：Qian, Yimin; Corbett, Wendy L.; Berthel, Steven J.; Choi, Duk Soon; Dvorozniak, Mark T.; Geng, Wanping; Gillespie, Paul; Guertin, Kevin R.; Haynes, Nancy-Ellen; Kester, Robert F.; Mennona, Francis A.; Moore, David; Racha, Jagdish; Radinov, Roumen; Sarabu, Ramakanth; Scott, Nathan R.; Grimsby, Joseph; Mallalieu, Navita L. ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 4 p. 414 - 418

29943-42-8 ~% 57385-16-7

文献：Gronnier, Colombe; Boissonnat, Guillaume; Gagosz, Fabien Organic Letters, 2013 , vol. 15, # 16 p. 4234 - 4237

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