41808-35-9

• 常用中文名：3-甲基-4-氰基-5-氨基异噻唑
• 常用英文名：5-Amino-3-methylisothiazole-4-carbonitrile
• CAS号：41808-35-9
• 分子式：C₅H₅N₃S
• 分子量：139.178
• 发布时间：2018-11-24 18:20:46
• 更新时间：2024-01-13 15:29:34

名称

• 中文名: 3-甲基-4-氰基-5-氨基异噻唑
• 英文名: 5-amino-3-methyl-1,2-thiazole-4-carbonitrile
• 中文别名: 5-氨基-3-甲基-4-氰基异噻唑; 5-氨基-4-氰基-3-甲基异噻唑
• 英文别名: 5-Amino-3-methyl-1,2-thiazole-4-carbonitrile; 5-Amino-3-methylisothiazole-4-carbonitrile; 5-amino-3-methyl-4-isothiazolecarbonitrile; 5-Amino-3-methyl-isothiazole-4-carbonitrile; 4-Isothiazolecarbonitrile, 5-amino-3-methyl-; 5-amino-4-cyano-3-methyl-isothiazole

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 198.6±40.0 °C at 760 mmHg
• 熔点: 202 °C
• 分子式: C₅H₅N₃S
• 分子量: 139.178
• 闪点: 73.9±27.3 °C
• 精确质量: 139.020416
• PSA: 90.94000
• LogP: 0.45
• 外观性状: 黄色至棕色固体
• 蒸汽压: 0.4±0.4 mmHg at 25°C
• 折射率: 1.610
• 储存条件: 2-8°C

安全

• 海关编码: 2934999090

合成路线

41808-30-4 ~50% 41808-35-9

文献：INTERMUNE, INC.; BUCKMAN, Brad, O.; NICHOLAS, John, B.; EMAYAN, Kumaraswamy; SEIWERT, Scott, D. Patent: WO2013/25733 A1, 2013 ; Location in patent: Paragraph 0436 ;

758721-53-8 ~81% 41808-35-9

文献：Theoclitou, Maria-Elena; Aquila, Brian; Block, Michael H.; Brassil, Patrick J.; Castriotta, Lillian; Code, Erin; Collins, Michael P.; Davies, Audrey M.; Deegan, Tracy; Ezhuthachan, Jayachandran; Filla, Sandra; Freed, Ellen; Hu, Haiqing; Huszar, Dennis; Jayaraman, Muthusamy; Lawson, Deborah; Lewis, Paula M; Nadella, Murali V. P.; Oza, Vibha; Padmanilayam, Maniyan; Pontz, Timothy; Ronco, Lucienne; Russell, Daniel; Whitston, David; Zheng, Xiaolan Journal of Medicinal Chemistry, 2011 , vol. 54, # 19 p. 6734 - 6750

5417-82-3 ~% 41808-35-9

文献：INTERMUNE, INC.; BUCKMAN, Brad, O.; NICHOLAS, John, B.; EMAYAN, Kumaraswamy; SEIWERT, Scott, D. Patent: WO2013/25733 A1, 2013 ;

49779-27-3 ~% 41808-35-9

文献：Goerdeler,J.; Pohland,H.W. Chemische Berichte, 1963 , vol. 96, p. 526 - 533

116595-42-7 ~% 41808-35-9

文献：Theoclitou, Maria-Elena; Aquila, Brian; Block, Michael H.; Brassil, Patrick J.; Castriotta, Lillian; Code, Erin; Collins, Michael P.; Davies, Audrey M.; Deegan, Tracy; Ezhuthachan, Jayachandran; Filla, Sandra; Freed, Ellen; Hu, Haiqing; Huszar, Dennis; Jayaraman, Muthusamy; Lawson, Deborah; Lewis, Paula M; Nadella, Murali V. P.; Oza, Vibha; Padmanilayam, Maniyan; Pontz, Timothy; Ronco, Lucienne; Russell, Daniel; Whitston, David; Zheng, Xiaolan Journal of Medicinal Chemistry, 2011 , vol. 54, # 19 p. 6734 - 6750

89943-20-4 ~% 41808-35-9

文献：INTERMUNE, INC.; BUCKMAN, Brad, O.; NICHOLAS, John, B.; EMAYAN, Kumaraswamy; SEIWERT, Scott, D. Patent: WO2013/25733 A1, 2013 ;

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%