82413-23-8

• 常用中文名：4′-羟基他莫昔芬-d6
• 常用英文名：4’-hydroxy Tamoxifen
• CAS号：82413-23-8
• 分子式：C₂₆H₂₉NO₂
• 分子量：387.51400
• 发布时间：2017-09-02 18:45:04
• 更新时间：2026-08-15 22:50:16
• 4’-hydroxy Tamoxifen is one of five main phase I metabolites of tamoxifen , a well-known estrogen receptor antagonist in breast but partial estrogen receptor agonist in endometrium.

名称

• 中文名: 4′-羟基他莫昔芬-d6
• 英文名: 4’-Hydroxy Tamoxifen
• 中文别名: 枸橼酸他莫昔芬杂质13 (4'-羟基他莫昔芬); 枸橼酸他莫昔芬杂质13
• 英文别名: Tamoxifen Citrate Impurity 13 (4'-Hydroxytamoxifen); 4'-Hydroxytamoxifen; trans-4'-hydroxytamoxifen; 4'-Hydroxy TaMoxifen (contains up to E isoMer); 4-[(1Z)-1-[[4-[2-(Dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]phenol; Tamoxifen Citrate Impurity 18; Phenol, 4-[(1Z)-1-[[4-[2-(dimethylamino)ethoxy]phenyl]phenylmethylene]propyl]

物化性质

• 熔点: 150-153ºC
• 分子式: C₂₆H₂₉NO₂
• 分子量: 387.51400
• 精确质量: 387.22000
• PSA: 32.70000
• LogP: 5.70170
• 储存条件: -20°C，密闭，干燥

合成路线

24845-40-7 ~% 82413-23-8

文献：Journal of Medicinal Chemistry, , vol. 25, # 9 p. 1056 - 1060

106-41-2 ~% 82413-23-8

文献：Journal of Medicinal Chemistry, , vol. 25, # 9 p. 1056 - 1060

35258-39-0 ~% 82413-23-8

文献：Journal of Medicinal Chemistry, , vol. 25, # 9 p. 1056 - 1060

82413-28-3 ~% 82413-23-8

文献：Journal of Medicinal Chemistry, , vol. 25, # 9 p. 1056 - 1060

2474-07-9 82413-31-8 ~% 82413-23-8 82413-21-6

文献：Journal of Medicinal Chemistry, , vol. 25, # 9 p. 1056 - 1060

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24845-40-7 106-41-2 35258-39-0 82413-28-3
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