571186-92-0

• 常用中文名：伊马替尼(吡啶)-N-氧化物
• 常用英文名：Imatinib (Pyridine)-N-Oxide
• CAS号：571186-92-0
• 分子式：C₂₉H₃₁N₇O₂
• 分子量：509.6
• 相关类别： 原料药 抗肿瘤药 替尼类抗肿瘤药
• 发布时间：2018-09-14 18:49:02
• 更新时间：2026-07-10 06:41:17

名称

• 中文名: 伊马替尼杂质F
• 英文名: N-[4-methyl-3-[[4-(1-oxidopyridin-1-ium-3-yl)pyrimidin-2-yl]amino]phenyl]-4-[(4-methylpiperazin-1-yl)methyl]benzamide
• 中文别名: 伊马替尼杂质19; 3-(2-((2-甲基-5-(4-((4-甲基哌嗪-1-基)甲基)苯甲酰胺基)苯基)氨基)嘧啶-4-基)吡啶1-氧化物(伊马替尼杂质); 甲磺酸伊马替尼杂质19; 伊马替尼吡啶N-氧化物(伊马替尼杂质69); 伊马替尼(吡啶)N-氧化物; 甲磺酸伊马替尼杂质19(伊马替尼吡啶N-氧化物); 伊马替尼杂质19(伊马替尼吡啶N-氧化物)
• 英文别名: 3-(2-((2-methyl-5-(4-((4-methylpiperazin-1-yl)methyl)benzamido)phenyl)amino)pyrimidin-4-yl)pyridine 1-oxide; Imatinib Impurity 1; Imatinib Imp.A; Imatinib Mesylate Impurity 19 (Imatinib Pyridine N-Oxide); 3-{2-[(2-methyl-5-{4-[(4-methylpiperazin-1-yl)methyl]benzamido}phenyl)amino]pyrimidin-4-yl}pyridin-1-ium-1-olate; N-(4-methyl-3-{[4-(1-oxidopyridin-3-yl)pyrimidin-2-yl]amino}; N-[4-Methyl-3-[[4-(1-oxido-3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-4-[(4-methyl-1-piperazinyl)methyl]benzamide; Imatinib (Pyridine)-N-oxide; amino)pyrimidin-4-yl)pyridine 1-oxide; 3-(2-((2-methyl-5-(4-((4-methylpiperazin-1-yl)methyl)benzamido)phenyl)amino)pyrimidin-4-yl)pyridine 1-oxide (Imatinib Impurity）; Imatinib Impurity 19 (Imatinib Pyridine N-Oxide); 3-(2-((2-methyl-5-(4-((4-methylpiperazin-1-yl); N-[4-METHYL-3-[[4-(1-OXIDO-PYRIDIN-3-YL)-PYRIMIDIN-2-YL]AMINO]PHENYL]-4-[(4-METHYL-(PIPERAZIN-1-YL))METHYL]BENZAMIDE; pyrimidin-4-yl)pyridine 1-oxide; Imatinib (Pyridine)-N-oxide //BP; Imatinib Mesylate Impurity 19; Benzamide, N-[4-methyl-3-[[4-(1-oxido-3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-4-[(4-methyl-1-piperazinyl)methyl]; Imatinib impurity 10/Imatinib (Pyridine)-N-Oxide/N-[4-Methyl-3-[[4-(1-oxido-3-pyridinyl)-2-pyrimidinyl]amino]phenyl]-4-[(4-methyl-1-piperazinyl)methyl]benzamide

物化性质

• 密度: 1.273g/cm3
• 熔点: 226-236ºC
• 分子式: C₂₉H₃₁N₇O₂
• 分子量: 509.6
• 精确质量: 509.25392326
• PSA: 99.69000
• LogP: 4.19850
• 折射率: 1.666
• 储存条件: -20°C Freezer