412348-60-8

• 常用中文名：1-BOC-4-(5-溴吡啶-3-基)哌嗪
• 常用英文名：tert-butyl 4-(5-bromopyridin-3-yl)piperazine-1-carboxylate
• CAS号：412348-60-8
• 分子式：C₁₄H₂₀BrN₃O₂
• 分子量：342.23200
• 发布时间：2018-12-04 20:31:52
• 更新时间：2025-09-18 18:41:55

名称

• 中文名: 1-Boc-4-(5-溴吡啶-3-基)哌嗪
• 英文名: tert-butyl 4-(5-bromopyridin-3-yl)piperazine-1-carboxylate
• 中文别名: 1-BOC-4-(5-溴-3-吡啶基)哌嗪; 4-(5-溴吡啶-3-基)哌嗪-1-羧酸叔丁酯
• 英文别名: 4-(5-Bromo-3-pyridinyl)-1-piperazinecboxylic acid tert-butyl ester; 1-(5-Bromo-3-pyridyl)-4-tert-butoxycbonylpiperazine; 1-(5-Bromo-3-pyridyl)-4-tert-butoxycarbonylpiperazine; 1-Boc-4-(5-bromo-3-pyridyl)piperazine; tert-butyl 4-(5-bromopyridin-3-yl)piperazine-1-cboxylate; 1-Piperazinecboxylic acid, 4-(5-bromo-3-pyridinyl)-, 1,1-dimethylethyl ester; 1-Boc-4-(5-BroMopyridin-3-yl)piperazine; 4-(5-bromo-pyridin-3-yl)-piperazine-1-carboxylic acid tert-butyl ester

物化性质

• 分子式: C₁₄H₂₀BrN₃O₂
• 分子量: 342.23200
• 精确质量: 341.07400
• PSA: 45.67000
• LogP: 2.90410

合成路线

233770-01-9 57260-71-6 ~38% 412348-60-8

文献：Xue, Chu-Biao; Zheng, Changsheng; Feng, Hao; Xia, Michael; Glenn, Joseph; Cao, Ganfeng.; Metcalf, Brian W. Patent: US2006/4018 A1, 2006 ; Location in patent: Page/Page column 27-28 ; US 20060004018 A1

625-92-3 57260-71-6 ~77% 412348-60-8

文献：Kono, Mitsunori; Matsumoto, Takahiro; Imaeda, Toshihiro; Kawamura, Toru; Fujimoto, Shinji; Kosugi, Yohei; Odani, Tomoyuki; Shimizu, Yuji; Matsui, Hideki; Shimojo, Masato; Kori, Masakuni Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 4 p. 1468 - 1478

412347-30-9 24424-99-5 ~89% 412348-60-8

文献：Audouze, Karine; Nielsen, Elsebet stergaard; Olsen, Gunnar M.; Ahring, Philip; Jorgensen, Tino Dyhring; Peters, Dan; Liljefors, Tommy; Balle, Thomas Journal of Medicinal Chemistry, 2006 , vol. 49, # 11 p. 3159 - 3171

625-92-3 224311-51-7 57260-71-6 ~20% 412348-60-8

文献：Li, Qun; Woods, Keith W.; Zhu, Gui-Dong; Fischer, John P.; Gong, Jianchun; Li, Tongmei; Gandhi, Virajkumar; Thomas, Sheela A.; Packard, Garrick K.; Song, Xiaohong; Abrams, Jason N.; Diebold, Robert; Dinges, Jurgen; Hutchins, Charles; Stoll, Vincent S.; Rosenberg, Saul H.; Giranda, Vincent L. Patent: US2003/187026 A1, 2003 ; US 20030187026 A1

625-92-3 ~% 412348-60-8

文献：Audouze, Karine; Nielsen, Elsebet stergaard; Olsen, Gunnar M.; Ahring, Philip; Jorgensen, Tino Dyhring; Peters, Dan; Liljefors, Tommy; Balle, Thomas Journal of Medicinal Chemistry, 2006 , vol. 49, # 11 p. 3159 - 3171

上下游产品

上游产品  6
233770-01-9 57260-71-6 625-92-3 412347-30-9
24424-99-5 224311-51-7
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