13344-50-8

• 常用中文名：Acetic acid,2-(methylnitrosoamino)-, ethyl ester
• 常用英文名：Acetic acid,2-(methylnitrosoamino)-, ethyl ester
• CAS号：13344-50-8
• 分子式：C₅H₁₀N₂O₃
• 分子量：146.14400
• 发布时间：2016-03-17 19:14:03
• 更新时间：2024-01-03 17:15:37

名称

• 英文名: ethyl 2-[methyl(nitroso)amino]acetate
• 英文别名: N-Methyl-N-nitroso-glycin-aethylester; N-methyl-N-nitroso-glycine ethyl ester; N-Nitrososarcosine,ethyl ester; N-Nitroso-sarkosin-aethylester; Nitrososarcosine ethyl ester; Sarcosine,N-nitroso-,ethyl ester; Ethyl (methylnitrosoamino)-acetate; Ethyl-N-nitrososarcosinate; N-Nitroso-N-methyl-glycin-ethylester; Nitroso-sarkosin-aethylester

物化性质

• 密度: 1.14g/cm3
• 沸点: 253.3ºC at 760mmHg
• 分子式: C₅H₁₀N₂O₃
• 分子量: 146.14400
• 闪点: 107ºC
• 精确质量: 146.06900
• PSA: 58.97000
• LogP: 0.16270
• 蒸汽压: 0.0184mmHg at 25°C
• 折射率: 1.465

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : VQ3325000 CHEMICAL NAME : Sarcosine, N-nitroso-, ethyl ester CAS REGISTRY NUMBER : 13344-50-8 BEILSTEIN REFERENCE NO. : 1768504 LAST UPDATED : 199612 DATA ITEMS CITED : 9 MOLECULAR FORMULA : C5-H10-N2-O3 MOLECULAR WEIGHT : 146.17 WISWESSER LINE NOTATION : ONN1&1VO2 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 4 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ZEKBAI Zeitschrift fuer Krebsforschung. (Berlin, Fed. Rep. Ger.) V.1-75, 1903-71. For publisher information, see JCROD7. Volume(issue)/page/year: 69,103,1967 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 4 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ZEKBAI Zeitschrift fuer Krebsforschung. (Berlin, Fed. Rep. Ger.) V.1-75, 1903-71. For publisher information, see JCROD7. Volume(issue)/page/year: 69,103,1967 ** TUMORIGENIC DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 4 gm/kg/16W-C TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors REFERENCE : CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 47,179,1989 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 3900 mg/kg/39W-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors REFERENCE : ZEKBAI Zeitschrift fuer Krebsforschung. (Berlin, Fed. Rep. Ger.) V.1-75, 1903-71. For publisher information, see JCROD7. Volume(issue)/page/year: 69,103,1967 TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 160 gm/kg/8W-I TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors REFERENCE : JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 71,75,1983 TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 9700 mg/kg/28W-C TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 19,1077,1969 TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 21 gm/kg/8W-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors REFERENCE : PUMTAG Trace Substances in Environmental Health. Proceedings of University of Missouri's Annual Conference on Trace Substances in Environmental Health. (Environmental Trace Substances Research Center, Univ. of Missouri, Columbia, MO 65201) V.1- 1967- Volume(issue)/page/year: 16,355,1982 TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 7900 mg/kg/23W-C TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors REFERENCE : NATWAY Naturwissenschaften. (Springer-Verlag, Heidelberger Platz 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.1- 1913- Volume(issue)/page/year: 50,99,1963 TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 4250 mg/kg/17W-C TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors REFERENCE : EKSODD Eksperimental'naya Onkologiya. Experimental Oncology. (V/O Mezhdunarodnaya Kniga, 113095 Mosow, USSR) V.1- 1979- Volume(issue)/page/year: 11(2),19,1989

安全

• 海关编码: 2922499990

合成路线

52605-49-9 ~91% 13344-50-8

文献：Johnston; McCaleb Synthesis, 1984 , vol. NO. 4, p. 311 - 313

13200-60-7 ~% 13344-50-8

文献：McElvain; Laughton Journal of the American Chemical Society, 1951 , vol. 73, p. 448,451

13200-60-7 80-11-5 ~% 13344-50-8 640-61-9

文献：Garcia-Rio, Luis; Iglesias, Emilia; Leis, J. Ramon; Pena, M. Elena; Rios, Ana Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1993 , # 1 p. 29 - 37

上下游产品

上游产品  3
52605-49-9 13200-60-7 80-11-5
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海关

海关编码	2922499990
中文概述	2922499990 其他氨基酸及其酯及它们的盐（含有一种以上含氧基的除外）. 增值税率:17.0% 退税率:9.0% 监管条件:AB(入境货物通关单,出境货物通关单) 最惠国关税:6.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装
监管条件	A.入境货物通关单 B.出境货物通关单
检验检疫	P.进境动植物、动植物产品检疫 Q.出境动植物、动植物产品检疫 R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验
Summary	HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%