525-26-8

• 常用中文名：2,4(1H,3H)-Quinazolinedione,3-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-, hydrochloride (1:1)
• 常用英文名：2,4(1H,3H)-Quinazolinedione,3-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-, hydrochloride (1:1)
• CAS号：525-26-8
• 分子式：C₂₁H₂₄Cl₂N₄O₂
• 分子量：435.34700
• 发布时间：2016-10-17 08:47:30
• 更新时间：2024-02-08 13:05:18

名称

• 英文名: 3-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-1H-quinazoline-2,4-dione,hydrochloride
• 英文别名: 2,4(1H,3H)-Quinazolinedione,3-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-,monohydrochloride; CLOPERIDONE HYDROCHLORIDE; MA 1337; 3-(3-(4-(m-Chlorophenyl)-1-piperazinyl)propyl)-2,4(1H,3H)-quinazolinedione hydrochloride; Cloperidone HCl; Cloperidone hydrochloride [USAN]

物化性质

• 沸点: 606.7ºC at 760mmHg
• 分子式: C₂₁H₂₄Cl₂N₄O₂
• 分子量: 435.34700
• 闪点: 320.7ºC
• 精确质量: 434.12800
• PSA: 61.34000
• LogP: 3.36040

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : VA1399500 CHEMICAL NAME : 2,4(1H,3H)-Quinazolinedione, 3-(3-(4-(m-chlorophenyl)-1-piperazinyl)propyl)-, monohydrochloride CAS REGISTRY NUMBER : 525-26-8 LAST UPDATED : 198605 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C21-H23-Cl-N4-O2.Cl-H MOLECULAR WEIGHT : 435.39 WISWESSER LINE NOTATION : T66 BMVNVJ D3- AT6N DNTJ DR CG &GH HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 7650 mg/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - respiratory depression REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 148,151,1965 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 3290 mg/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - respiratory depression REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 148,151,1965 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2610 mg/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - respiratory depression REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 148,151,1965