4943-86-6

• 常用中文名：2-氨基-N-(4-氯苯基)苯甲酰胺
• 常用英文名：2-(4-Chlorophenylcarbamyl)aniline
• CAS号：4943-86-6
• 分子式：C₁₃H₁₁ClN₂O
• 分子量：246.692
• 发布时间：2018-12-24 12:23:10
• 更新时间：2024-01-05 10:59:28
• CP-74006 is a selective D5D inhibitor. CP-74006 potently blocks the Delta5D activity with an IC(50) value of 20 nM and simplifies the metabolism of [1-(14)C]-alpha-linolenate (C18:3, cis-9,12,15) by accumulating (14)C-eicosatetraenoic acid (C20:4, cis-8,11,14,17) as the major (14)C-eicosatrienoic acid (C20:3, cis-11,14,17) and (14)C-docosatetraenoic acid (C22:4, cis-10,13,16,19) as the minor metabolites through Delta6 desaturation and elongation.

名称

• 中文名: 2-氨基-N-(4-氯苯基)苯甲酰胺
• 英文名: 2-Amino-N-(4-chlorophenyl)benzamide
• 中文别名: 2-氨基-N-(4-氯苯基)-苯甲酰胺
• 英文别名: N1-(4-chlorophenyl)-2-aminobenzamide; 2-Amino-N-(4-chloro-phenyl)-benzamide; Benzamide, 2-amino-N-(4-chlorophenyl)-; antranil 4-chloroanilide; 2-Amino-N-(4-chlorophenyl)benzamide; 2-(4-Chlorophenylcarbamyl)aniline

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 337.2±27.0 °C at 760 mmHg
• 分子式: C₁₃H₁₁ClN₂O
• 分子量: 246.692
• 闪点: 157.7±23.7 °C
• 精确质量: 246.055984
• PSA: 55.12000
• LogP: 3.17
• 蒸汽压: 0.0±0.7 mmHg at 25°C
• 折射率: 1.692
• 储存条件: 室温，干燥

安全

• 海关编码: 2924299090

合成路线

41562-57-6 ~89% 4943-86-6

文献：Kakuta, Hiroki; Zheng, Xiaoxia; Oda, Hiroyuki; Harada, Shun; Sugimoto, Yukio; Sasaki, Kenji; Tai, Akihiro Journal of Medicinal Chemistry, 2008 , vol. 51, # 8 p. 2400 - 2411

118-48-9 106-47-8 ~86% 4943-86-6

文献：Dabiri; Salehi; Mohammadi, Ali A.; Baghbanzadeh; Kozehgiry, Gh. Journal of Chemical Research, 2004 , # 8 p. 570 - 572

610-14-0 ~% 4943-86-6

文献：Chou, Yuo-Ling; Davey, David D.; Eagen, Keith A.; Griedel, Brian D.; Karanjawala, Rushad; Phillips, Gary B.; Sacchi, Karna L.; Shaw, Kenneth J.; Wu, Shung C.; Lentz, Dao; Liang, Amy M.; Trinh, Lan; Morrissey, Michael M.; Kochanny, Monica J. Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 3 p. 507 - 511

106-47-8 ~% 4943-86-6

文献：Mendel, David; Marquart, Angela L.; Joseph, Sajan; Waid, Philip; Yee, Ying K.; Tebbe, Anne Louise; Ratz, Andrew M.; Herron, David K.; Goodson, Theodore; Masters, John J.; Franciskovich, Jeffry B.; Tinsley, Jennifer M.; Wiley, Michael R.; Weir, Leonard C.; Kyle, Jeffrey A.; Klimkowski, Valentine J.; Smith, Gerald F.; Towner, Richard D.; Froelich, Larry L.; Buben, John; Craft, Trelia J. Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 17 p. 4832 - 4836

552-16-9 ~% 4943-86-6

文献：Chou, Yuo-Ling; Davey, David D.; Eagen, Keith A.; Griedel, Brian D.; Karanjawala, Rushad; Phillips, Gary B.; Sacchi, Karna L.; Shaw, Kenneth J.; Wu, Shung C.; Lentz, Dao; Liang, Amy M.; Trinh, Lan; Morrissey, Michael M.; Kochanny, Monica J. Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 3 p. 507 - 511

118-92-3 ~% 4943-86-6

文献：Clark; Wagner Journal of Organic Chemistry, 1944 , vol. 9, p. 55,61, 63

118-48-9 91-56-5 106-47-8 ~% 1158178-11-0 详细

文献：Mohammadi, Ali A.; Dabiri; Qaraat Tetrahedron, 2009 , vol. 65, # 18 p. 3804 - 3808

上下游产品

上游产品  7
41562-57-6 118-48-9 106-47-8 610-14-0
552-16-9 118-92-3 91-56-5
下游产品  2
1788-93-8 24122-31-4

海关

海关编码	2924299090
中文概述	2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 包装
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%