477933-12-3

• 常用中文名：1-(2-环丙基乙基) -6-氟-2H-3,1-苯并噁嗪-2,4-二酮
• 常用英文名：1-(2-CYANOPHENYL)METHANESULFONAMIDE
• CAS号：477933-12-3
• 分子式：C₁₃H₁₂FNO₃
• 分子量：249.23800
• 发布时间：2018-12-29 19:43:39
• 更新时间：2026-07-03 20:18:50

名称

• 中文名: 1-(2-环丙基乙基) -6-氟-2H-3,1-苯并噁嗪-2,4-二酮
• 英文名: 1-(2-cyclopropylethyl)-6-fluoro-3,1-benzoxazine-2,4-dione
• 中文别名: 1-(2-环丙基乙基)-6-氟-1H-苯并[d][1,3]噁嗪-2,4-二酮; 1-(2-环丙基乙基)-6-氟-2H-苯并[D][1,3]噁嗪-2,4(1H)-二酮
• 英文别名: 1-(2-Cyclopropylethyl)-6-fluorobenzo[d][1,3]oxazine-2,4-dione; 1-(2-CYCLOPROPYL-ETHYL)-6-FLUORO-1H-BENZO[D][1,3]OXAZINE-2,4-DIONE; 1-(2-Cyclopropylethyl)-6-fluoro-2H-benzo[d][1,3]oxazine-2,4(1H)-dione; 1-(2-Cyclopropylethyl)-6-fluoro-2H-3,1-benzoxazine-2,4(1H)-dione; 2H-3,1-Benzoxazine-2,4(1H)-dione, 1-(2-cyclopropylethyl)-6-fluoro

物化性质

• 分子式: C₁₃H₁₂FNO₃
• 分子量: 249.23800
• 精确质量: 249.08000
• PSA: 52.21000
• LogP: 1.89390

合成路线

321-69-7 2566-44-1 ~83% 477933-12-3

文献：Idenix Pharmaceuticals, Inc. Patent: US2009/60866 A1, 2009 ; Location in patent: Page/Page column 52; 56 ;

446-08-2 ~% 477933-12-3

文献：Tedesco, Rosanna; Shaw, Antony N.; Bambal, Ramesh; Chai, Deping; Concha, Nestor O.; Darcy, Michael G.; Dhanak, Dashyant; Fitch, Duke M.; Gates, Adam; Gerhardt, Warren G.; Halegoua, Dina L.; Han, Chao; Hofmann, Glenn A.; Johnston, Victor K.; Kaura, Arun C.; Liu, Nannan; Keenan, Richard M.; Lin-Goerke, Juili; Sarisky, Robert T.; Wiggall, Kenneth J.; Zimmerman, Michael N.; Duffy, Kevin J. Journal of Medicinal Chemistry, 2006 , vol. 49, # 3 p. 971 - 983

32315-10-9 477932-69-7 ~% 477933-12-3

文献：Hendricks, Robert T.; Fell, Jay B.; Blake, James F.; Fischer, John P.; Robinson, John E.; Spencer, Stacey R.; Stengel, Peter J.; Bernacki, April L.; Leveque, Vincent J.P.; Pogam, Sophie Le; Rajyaguru, Sonal; Najera, Isabel; Josey, John A.; Harris, Jason R.; Swallow, Steven Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 13 p. 3637 - 3641

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