84332-26-3

• 常用中文名：5-Pyrimidinecarboxamide, N-((1-benzyl-2-pyrrolidinyl)methyl)-2-(dimeth ylamino)-4-methoxy-, dihydrochloride
• 常用英文名：5-Pyrimidinecarboxamide, N-((1-benzyl-2-pyrrolidinyl)methyl)-2-(dimeth ylamino)-4-methoxy-, dihydrochloride
• CAS号：84332-26-3
• 分子式：C₂₀H₂₉Cl₂N₅O₂
• 分子量：442.38300
• 发布时间：2018-06-26 15:21:27
• 更新时间：2024-01-09 12:46:43

名称

• 英文名: N-[(1-benzylpyrrolidin-2-yl)methyl]-2-(dimethylamino)-4-methoxypyrimidine-5-carboxamide,dihydrochloride
• 英文别名: N-[(1-benzylpyrrolidin-2-yl)methyl]-2-(dimethylamino)-4-methoxypyrimidine-5-carboxamide dihydrochloride; 5-Pyrimidinecarboxamide,N-((1-benzyl-2-pyrrolidinyl)methyl)-2-(dimethylamino)-4-methoxy-,dihydrochloride

物化性质

• 沸点: 603.7ºC at 760 mmHg
• 分子式: C₂₀H₂₉Cl₂N₅O₂
• 分子量: 442.38300
• 闪点: 318.9ºC
• 精确质量: 441.17000
• PSA: 74.08000
• LogP: 4.06230

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UV7707200 CHEMICAL NAME : 5-Pyrimidinecarboxamide, N-((1-benzyl-2-pyrrolidinyl)methyl)-2-(dimethylamino) -4-methoxy-, dihydrochloride CAS REGISTRY NUMBER : 84332-26-3 LAST UPDATED : 198609 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C20-H27-N5-O2.2Cl-H MOLECULAR WEIGHT : 442.44 WISWESSER LINE NOTATION : T6N CNJ BN1&1 DO1 EVM1- BT5NTJ A1R &GH 2 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 115 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 17,437,1982

合成路线

54127-87-6 ~% 84332-26-3

文献：Dostert; Imbert; Ancher; et al. European Journal of Medicinal Chemistry, 1982 , vol. 17, # 5 p. 437 - 444

72411-80-4 ~% 84332-26-3

文献：Dostert; Imbert; Ancher; et al. European Journal of Medicinal Chemistry, 1982 , vol. 17, # 5 p. 437 - 444

54127-88-7 ~% 84332-26-3

文献：Dostert; Imbert; Ancher; et al. European Journal of Medicinal Chemistry, 1982 , vol. 17, # 5 p. 437 - 444

53554-29-3 ~% 84332-26-3

文献：Dostert; Imbert; Ancher; et al. European Journal of Medicinal Chemistry, 1982 , vol. 17, # 5 p. 437 - 444

57734-44-8 72411-90-6 ~% 84332-26-3

文献：Dostert; Imbert; Ancher; et al. European Journal of Medicinal Chemistry, 1982 , vol. 17, # 5 p. 437 - 444

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