859538-41-3

• 常用中文名：5-(二氟甲基)吡啶-2-甲酸
• 常用英文名：5-(difluoromethyl)picolinic acid
• CAS号：859538-41-3
• 分子式：C₇H₅F₂NO₂
• 分子量：173.11700
• 发布时间：2018-07-11 16:46:37
• 更新时间：2024-01-27 20:23:39

名称

• 中文名: 5-(二氟甲基)-2-吡啶羧酸
• 英文名: 5-(Difluoromethyl)-2-pyridinecarboxylic acid
• 英文别名: 5-Difluoromethyl-2-fluoro-nitrobenzene; 5-difluoromethyl-pyridine-2-carboxylic acid

物化性质

• 分子式: C₇H₅F₂NO₂
• 分子量: 173.11700
• 精确质量: 173.02900
• PSA: 50.19000
• LogP: 1.71740
• 储存条件: 2-8°C， 惰性气体

合成路线

1346148-42-2 ~63% 859538-41-3

文献：Banner, David; Guba, Wolfgang; Hilpert, Hans; Humm, Roland; Mauser, Harald; Mayweg, Alexander V.; Narquizian, Robert; Power, Eoin; Rogers-Evans, Mark; Rombach, Didier; Woltering, Thomas; Wostl, Wolfgang Patent: US2011/312937 A1, 2011 ; Location in patent: Page/Page column 83-84 ;

1221272-81-6 ~% 859538-41-3

文献：F. HOFFMANN-LA ROCHE AG; SIENA BIOTECH S.P.A.; BANNER, David; GUBA, Wolfgang; HILPERT, Hans; HUMM, Roland; MAUSER, Harald; MAYWEG, Alexander, V.; NARQUIZIAN, Robert; POWER, Eoin; ROGERS-EVANS, Mark; ROMBACH, Didier; WOLTERING, Thomas; WOSTL, Wolfgang Patent: WO2011/138293 A1, 2011 ; WO 2011/138293 A1

149806-06-4 ~% 859538-41-3

文献：LEWIS, Richard T.; ALLEN, Jennifer R.; CHENG, Yuan; CHOQUETTE, Deborah; EPSTEIN, Oleg; GUZMAN-PEREZ, Angel; HARRINGTON, Paul E.; HUA, Zihao; HUNGATE, Randall W.; HUMAN, Jason Brooks; JUDD, Ted; LIU, Qingyian; LOPEZ, Patricia; MINATTI, Ana Elena; OLIVIERI, Philip; ROMERO, Karina; RUMFELT, Shannon; RZASA, Robert M.; SCHENKEL, Laurie; STELLWAGEN, John; WHITE, Ryan; XUE, Qiufen; ZHENG, Xiao; ZHONG, Wenge Patent: US2014/107109 A1, 2014 ;

131747-68-7 ~% 859538-41-3

文献：LEWIS, Richard T.; ALLEN, Jennifer R.; CHENG, Yuan; CHOQUETTE, Deborah; EPSTEIN, Oleg; GUZMAN-PEREZ, Angel; HARRINGTON, Paul E.; HUA, Zihao; HUNGATE, Randall W.; HUMAN, Jason Brooks; JUDD, Ted; LIU, Qingyian; LOPEZ, Patricia; MINATTI, Ana Elena; OLIVIERI, Philip; ROMERO, Karina; RUMFELT, Shannon; RZASA, Robert M.; SCHENKEL, Laurie; STELLWAGEN, John; WHITE, Ryan; XUE, Qiufen; ZHENG, Xiao; ZHONG, Wenge Patent: US2014/107109 A1, 2014 ;