102367-57-7

• 常用中文名：Vestphylline
• 常用英文名：Vestphylline
• CAS号：102367-57-7
• 分子式：C₂₅H₃₅N₅O₄
• 分子量：469.57700
• 发布时间：2016-02-25 04:05:40
• 更新时间：2024-02-02 13:29:56

名称

• 英文名: [1-[bis(2-methylpropyl)amino]-3-(1,3-dimethyl-2,6-dioxo-7H-purin-8-yl)propan-2-yl] benzoate
• 英文别名: Diisobutylaminobenzoyloxypropyl theophylline; Vestphyllin; Diisobutylaminobenzoyloxypropyl theophylline (JAN); 7-(3-Diisobutylamino-2-benzoyloxypropyl)theophylline

物化性质

• 密度: 1.2g/cm3
• 沸点: 634.2ºC at 760mmHg
• 分子式: C₂₅H₃₅N₅O₄
• 分子量: 469.57700
• 闪点: 337.3ºC
• 精确质量: 469.26900
• PSA: 102.22000
• LogP: 2.34240
• 蒸汽压: 0mmHg at 25°C
• 折射率: 1.591

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : XH5161000 CHEMICAL NAME : Theophylline-8-ethanol, alpha-((diisobutylamino)methyl)-, benzoate (ester) CAS REGISTRY NUMBER : 102367-57-7 LAST UPDATED : 199609 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C25-H35-N5-O4 MOLECULAR WEIGHT : 469.65 WISWESSER LINE NOTATION : T56 BM DN FNVNVJ C1YOVR&1N1Y1&1&1Y1&1 F1 H1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85IPAE "Modern Pharmaceuticals of Japan, III," Tokyo, Japan Pharmaceutical, Medical and Dental Supply Exporters' Assoc., 1968 Volume(issue)/page/year: -,101,1968 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1835 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,306,1982 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 273 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,306,1982