158144-82-2

• 常用中文名：1-N-Boc-4-氨基甲基-4-苯基哌啶
• 常用英文名：TERT-BUTYL 4-(AMINOMETHYL)-4-PHENYLPIPERIDINE-1-CARBOXYLATE
• CAS号：158144-82-2
• 分子式：C₁₇H₂₆N₂O₂
• 分子量：290.401
• 发布时间：2018-11-25 16:15:51
• 更新时间：2024-01-10 18:31:11

名称

• 中文名: 1-N-Boc-4-氨基甲基-4-苯基哌啶
• 英文名: tert-butyl 4-(aminomethyl)-4-phenylpiperidine-1-carboxylate
• 英文别名: 1-Piperidinecarboxylic acid, 4-(aminomethyl)-4-phenyl-, 1,1-dimethylethyl ester; tert-butyl 4-aminomethyl-4-phenylpiperidine-1-carboxylate; 1,1-dimethylethyl 4-aminomethyl-4-phenylpiperidine-1-carboxylate; 4-phenyl-4-aminomethyl-1-t-butoxycarbonyl piperidine; 1-N-BOC-4-AMINOMETHYL-4-PHENYLPIPERIDINE; 2-Methyl-2-propanyl 4-(aminomethyl)-4-phenyl-1-piperidinecarboxylate; 1-BOC-4-AMINOMETHYL-4-PHENYL-PIPERIDINE

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 402.7±38.0 °C at 760 mmHg
• 分子式: C₁₇H₂₆N₂O₂
• 分子量: 290.401
• 闪点: 197.3±26.8 °C
• 精确质量: 290.199432
• PSA: 55.56000
• LogP: 2.68
• 蒸汽压: 0.0±0.9 mmHg at 25°C
• 折射率: 1.530

合成路线

158144-79-7 ~82% 158144-82-2

文献：Stevenson, Graeme I.; Huscroft, Ian; MacLeod, Angus M.; Swain, Christopher J.; Cascieri, Margaret A.; Chicchi, Gary G.; Graham, Michael I.; Harrison, Timothy; Kelleher, Fintan J.; Kurtz, Marc; Ladduwahetty, Tamara; Merchant, Kevin J.; Metzger, Joseph M.; MacIntyre; Sadowski, Sharon; Sohal, Balbinder; Owens, Andrew P. Journal of Medicinal Chemistry, 1998 , vol. 41, # 23 p. 4623 - 4635

24424-99-5 ~% 158144-82-2

文献：Elliott; Broughton; Cascieri; Chicchi; Huscroft; Kurtz; MacLeod; Sadowski; Stevenson Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 14 p. 1851 - 1856

24424-99-5 51304-58-6 ~% 158144-82-2

文献：Dinnell, Kevin; Elliott, Jason Matthew; Hollingworth, Gregory John; Ridgill, Mark Peter; Shaw, Duncan Edward Patent: US2001/39286 A1, 2001 ;

51304-58-6 ~% 158144-82-2

文献：Stevenson, Graeme I.; Huscroft, Ian; MacLeod, Angus M.; Swain, Christopher J.; Cascieri, Margaret A.; Chicchi, Gary G.; Graham, Michael I.; Harrison, Timothy; Kelleher, Fintan J.; Kurtz, Marc; Ladduwahetty, Tamara; Merchant, Kevin J.; Metzger, Joseph M.; MacIntyre; Sadowski, Sharon; Sohal, Balbinder; Owens, Andrew P. Journal of Medicinal Chemistry, 1998 , vol. 41, # 23 p. 4623 - 4635

40481-13-8 ~% 158144-82-2

文献：Liu, Jian; Jian, Tianying; Sebhat, Iyassu; Nargund, Ravi Tetrahedron Letters, 2006 , vol. 47, # 29 p. 5115 - 5117