1112262-71-1

• 常用中文名：阿托伐他汀钙杂质52
• 常用英文名：2-((4R,6R)-6-(2-(3-(phenylcarbamoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic acid isopropyl ester
• CAS号：1112262-71-1
• 分子式：C₃₉H₄₅FN₂O₅
• 分子量：640.78300
• 发布时间：2016-06-13 09:17:39
• 更新时间：2026-08-21 17:17:23

名称

• 中文名: 阿托伐他汀钙杂质52
• 英文名: 2-((4R,6R)-6-(2-(3-(phenylcarbamoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic acid isopropyl ester
• 英文别名: Propan-2-yl [(4R,6R)-6-{2-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxan-4-yl]acetate; .2-((4R,6R)-6-(2-(3-(phenylcarbamoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic acid 1-methylethylester; 1,3-Dioxane-4-acetic acid, 6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-, 1-methylethyl ester, (4R,6R); isopropyl 2-((4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate; propan-2-yl 2-[(4R,6R)-6-{2-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxan-4-yl]acetate; isopropyl 2-((4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl- 4-(phenylcbamoyl)-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate; Atorvastatin calcium impurity 52; Atorvastatin Impurity

物化性质

• 分子式: C₃₉H₄₅FN₂O₅
• 分子量: 640.78300
• 精确质量: 640.33100
• PSA: 78.79000
• LogP: 9.05190

合成路线

1112262-76-6 125971-96-2 ~66% 1112262-71-1

文献：DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V.; LANGE, DE, Ben; ELSENBERG, Henricus, Leonardus, Marie Patent:   WO2012/32035 A1, 2012 ; Location in patent: Page/Page column 9 ;

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