CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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CE1050000
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CHEMICAL NAME :
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6a-alpha-Aporphin-11-ol, 10-methoxy-1,2-(methylenedioxy)-
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CAS REGISTRY NUMBER :
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298-45-3
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LAST UPDATED :
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199803
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DATA ITEMS CITED :
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3
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MOLECULAR FORMULA :
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C19-H19-N-O4
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MOLECULAR WEIGHT :
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325.39
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WISWESSER LINE NOTATION :
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T D56 J666 1A T EO GO RN FH&&&TTJ KQ LO1 R1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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145 mg/kg
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TOXIC EFFECTS :
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Autonomic Nervous System - smooth muscle relaxant (mechanism undefined, spasmolytic)
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REFERENCE :
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AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 155,69,1965
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Subcutaneous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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195 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 56,85,1936
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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79 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#12068
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