496-30-0

• 常用中文名：2-吲哚啉硫酮
• 常用英文名：3H-Indole-2-thiol
• CAS号：496-30-0
• 分子式：C₈H₇NS
• 分子量：149.213
• 发布时间：2019-02-20 16:42:00
• 更新时间：2024-01-14 13:09:58

名称

• 中文名: 1,3-二氢-2H-吲哚-2-硫酮
• 英文名: 1,3-dihydroindole-2-thione
• 中文别名: 2-吲哚啉硫酮
• 英文别名: Benzazoline-2-thione; 1,3-Dihydro-indole-2-thione; 3H-Indole-2-thiol; indoline-2-thione; indoline-1-thione; 2-INDOLINETHIONE; 1,3-Dihydro-2H-indole-2-thione; 2H-Indole-2-thione, 1,3-dihydro-; indole-2-thione

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 243.4±43.0 °C at 760 mmHg
• 分子式: C₈H₇NS
• 分子量: 149.213
• 闪点: 101.0±28.2 °C
• 精确质量: 149.029922
• PSA: 44.12000
• LogP: 1.46
• 蒸汽压: 0.0±0.5 mmHg at 25°C
• 折射率: 1.693
• 储存条件: 2-8°C， 干燥

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : NM2060000 CHEMICAL NAME : 2-Indolinethione CAS REGISTRY NUMBER : 496-30-0 BEILSTEIN REFERENCE NO. : 0002992 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C8-H7-N-S MOLECULAR WEIGHT : 149.22 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 37 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 94,1620,1974

合成路线

59-48-3 ~94% 496-30-0

文献：VIRONOVA AB; PETTERSSON, Birgitta; HASIMBEGOVIC, Vedran; SVENSSON, Per, H.; BERGMAN, Jan Patent: WO2012/104415 A1, 2012 ; Location in patent: Page/Page column 10 ;

13839-92-4 ~% 496-30-0

文献：VIRONOVA AB; PETTERSSON, Birgitta; HASIMBEGOVIC, Vedran; SVENSSON, Per, H.; BERGMAN, Jan Patent: WO2012/104415 A1, 2012 ; Location in patent: Page/Page column 9; 10 ;

91-56-5 ~% 496-30-0

文献：Thanigaimalai, Pillaiyar; Lee, Ki-Cheul; Sharma, Vinay Kumar; Sharma, Niti; Roh, Eunmiri; Kim, Youngsoo; Jung, Sang-Hun Chemical and Pharmaceutical Bulletin, 2011 , vol. 59, # 10 p. 1285 - 1288

587-65-5 ~% 496-30-0

文献：Sugasawa et al. Yakugaku Zasshi, 1938 , vol. 58, p. 139;engl.Ref.S.29 Chem.Abstr., 1938 , p. 4161

110994-15-5 ~21% 496-30-0

文献：Baudin, Jean-Bernard; Julia, Sylvestre A.; Lorne, Robert Bulletin de la Societe Chimique de France, 1987 , # 1 p. 181 - 188

120-72-9 ~55% 496-30-0

文献：Rewcastle, Gordon W; Janosik, Tomasz; Bergman, Jan Tetrahedron, 2001 , vol. 57, # 33 p. 7185 - 7189

上下游产品

上游产品  6
59-48-3 13839-92-4 91-56-5 587-65-5
110994-15-5 120-72-9
下游产品  9
496-15-1 91-56-5 126654-63-5 120-72-9
1484-19-1 73424-93-8 73425-59-9 91539-87-6
61021-91-8