106881-41-8

• 常用中文名：托吡酯杂质B
• 常用英文名：4,5-Desisopropylidene Topiramate
• CAS号：106881-41-8
• 分子式：C₉H₁₇NO₈S
• 分子量：299.29800
• 发布时间：2017-10-31 19:10:00
• 更新时间：2026-07-01 20:35:27

名称

• 中文名: 托吡酯杂质B
• 英文名: [(3aS,6R,7R,7aS)-6,7-dihydroxy-2,2-dimethyl-5,6,7,7a-tetrahydro-[1,3]dioxolo[4,5-b]pyran-3a-yl]methyl sulfamate
• 中文别名: 托吡酯粗品杂质5; 托吡酯去缩醛杂质(4,5-二醇-托吡酯); 托吡酯杂质3(托吡酯杂质C); 托吡酯杂质C; 2,3-O-(1-甲基亚乙基)-BETA-D-吡喃果糖1-氨基磺酸酯; ((3AS,6R,7R,7AS)-6,7-二羟基-2,2-二甲基四氢-3AH-[1,3]二氧代[4,5-B]吡喃-3A-基)氨基磺酸甲酯; 托吡酯脱乙缩醛杂质; 托吡酯4,5-去甲异亚丙基杂质; 托吡酯去乙酰杂质(4,5-二醇-托吡酯)
• 英文别名: β-D-Fructopyranose, 2,3-O-(1-methylethylidene)-, 1-sulfamate; TopiraMate Desacetal IMpurity; Topiramate Impurity B(IP); b-D-Fructopyranose,2,3-O-(1-methylethylidene)-, 1-sulfamate; Topiramte Impurity C; 2,3-O-(1-Methylethylidene)-D-fructopyranose 1-Sulfamate; Topiramate Impurity C (4,5-Diol Topiramate); Topiramate 4,5-Desisopropylidene Impurity; Topiramate Impurity 5; 2,3-O-(1-Methylethylidene)-beta-D-fructopyranose 1-sulfamate; ((3aS,6R,7R,7aS)-6,7-Dihydroxy-2,2-dimethyltetrahydro-3aH-[1,3]dioxolo[4,5-b]pyran-3a-yl)methyl sulfamate; Topiramate Impurity 3 (Topiramate Impurity C); Topiramate Desacetal Impurity (4,5-diol-Topiramate); 2,3-O-(1-Methylethylidene)-1-O-sulfamoyl-β-D-fructopyranose; 2,3-O-(1-Methylethylidene)-b-D-fructopyranose 1-Sulfamate; 2,3-O-(1-Methylethylidene)-|A-D-fructopyranose 1-Sulfamate; Topiramate Impurity C

物化性质

• 分子式: C₉H₁₇NO₈S
• 分子量: 299.29800
• 精确质量: 299.06700
• PSA: 145.92000

合成路线

97240-79-4 ~31% 106881-41-8

文献：Maryanoff, Bruce E.; Nortey, Samuel O.; Gardocki, Joseph F.; Shank, Richard P.; Dodgson, Susanna P. Journal of Medicinal Chemistry, 1987 , vol. 30, # 5 p. 880 - 887

20880-92-6 ~% 106881-41-8

文献：Journal of Medicinal Chemistry, , vol. 30, # 5 p. 880 - 887

上下游产品

上游产品  2
97240-79-4 20880-92-6
下游产品  1
97240-79-4