6975-73-1

• 常用中文名：异烟肼氧化氮
• 常用英文名：4-(hydrazinecarbonyl)pyridin-1-ium-1-olate
• CAS号：6975-73-1
• 分子式：C₆H₇N₃O₂
• 分子量：153.13900
• 发布时间：2017-07-13 05:20:58
• 更新时间：2026-07-05 18:11:36

名称

• 中文名: 异烟肼氧化氮
• 英文名: diazenyl-(1-hydroxypyridin-4-ylidene)methanol
• 中文别名: 托比司他杂质E,异烟肼氮氧化物; 异烟肼酰氮氧化物; 异烟肼氮氧化物; 托吡酯杂质E; 异烟酰肼N-氧化物; 托吡酯杂质1; 异烟肼-N-氧化物; 托匹司他14; 托匹司他Z14
• 英文别名: 4-Pyridinecboxylic acid, hydrazide, 1-oxide; isonicotinic acid hydrazide-N-oxide; 1-Oxy-isonicotinsaeure-hydrazid; 4-Pyridinecarboxylic acid,hydrazide,1-oxide; 1-oxy-isonicotinic acid hydrazide; 4-(hydrazinecbonyl)pyridin-1-ium-1-olate Isoniazide-N-oxide; Isoniazide-N-oxide; 4-(HYDRAZINECBONYL)PYRIDIN-1-IUM-1-OLATE; Topiroxostat impurity E; Topiroxostat Impurity I2; ISONICOTINIC ACID,HYDRAZIDE,1-OXIDE; 4-(hydrazinecbonyl)pyridine 1-oxide; Isoniazid Nitrogen Oxide; Topirastat Impurity D

物化性质

• 密度: 1.42g/cm3
• 沸点: 208.9ºC at 760 mmHg
• 分子式: C₆H₇N₃O₂
• 分子量: 153.13900
• 闪点: 80.1ºC
• 精确质量: 153.05400
• PSA: 80.58000
• LogP: 0.80980
• 折射率: 1.631
• 储存条件: 室温

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : NS1781000 CHEMICAL NAME : Isonicotinic acid, hydrazide, 1-oxide CAS REGISTRY NUMBER : 6975-73-1 BEILSTEIN REFERENCE NO. : 0136500 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C6-H7-N3-O2 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1675 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : APPHAX Acta Poloniae Pharmaceutica. For English translation, see APPFAR. (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland) V.1- 1937- Volume(issue)/page/year: 13,274,1956

合成路线

3783-38-8 ~% 6975-73-1

文献：Yale et al. Journal of the American Chemical Society, 1953 , vol. 75, p. 1933,1934 Show Details Bixler; Niemann Journal of the American Chemical Society, 1958 , vol. 80, p. 2716,2718

14906-37-7 ~% 6975-73-1

文献：Shimizu et al. Yakugaku Zasshi, 1952 , vol. 72, p. 1474,1476 Chem.Abstr., 1953 , p. 8077 Show Details Colonna; Runti Annali di Chimica (Rome, Italy), 1953 , vol. 43, p. 87,89

1570-45-2 ~% 6975-73-1

文献：Colonna; Runti Annali di Chimica (Rome, Italy), 1953 , vol. 43, p. 87,89

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