1458-63-5

• 常用中文名：N-(3-氯丙基)哌啶
• 常用英文名：1-(3-chloropropyl)piperidine
• CAS号：1458-63-5
• 分子式：C₈H₁₆ClN
• 分子量：161.672
• 发布时间：2018-08-19 11:36:14
• 更新时间：2024-01-03 07:37:21

名称

• 中文名: N-(3-氯丙基)哌啶
• 英文名: 1-(3-chloropropyl)piperidine
• 中文别名: 1-氯-3-哌啶基丙烷
• 英文别名: Piperidine, 1-(3-chloropropyl)-; 3-(piperidin-1-yl)propyl chloride; 3-(1-Piperidinyl)propyl chloride; 1-(3-chloropropyl)-piperidine; 3-piperidino-propyl chloride; Piperidine,1-(3-chloropropyl); 1-chloro-3-(1-piperidinyl)-propane; n-(3-chloropropyl)piperidine; N-(γ-Chloropropyl)piperidine; 1-(3-Chloropropyl)piperidine; N-(3-chloropropyl)-piperidine; HDDNBUNZJIQDBQ-UHFFFAOYSA; 3-chloropropylpiperidine

物化性质

• 密度: 1.0±0.1 g/cm3
• 沸点: 217.3±23.0 °C at 760 mmHg
• 分子式: C₈H₁₆ClN
• 分子量: 161.672
• 闪点: 85.2±22.6 °C
• 精确质量: 161.097122
• PSA: 3.24000
• LogP: 2.31
• 蒸汽压: 0.1±0.4 mmHg at 25°C
• 折射率: 1.470

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TM6498580 CHEMICAL NAME : Piperidine, 1-(3-chloropropyl)- CAS REGISTRY NUMBER : 1458-63-5 BEILSTEIN REFERENCE NO. : 0104061 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C8-H16-Cl-N HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 104 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : APPHAX Acta Poloniae Pharmaceutica. For English translation, see APPFAR. (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland) V.1- 1937- Volume(issue)/page/year: 33,169,1976

安全

• 海关编码: 2933399090

合成路线

5472-49-1 ~92% 1458-63-5

文献：Chen, Qingqi; Lopez, Rocio Alejandra; Heller, Jonathan Daniel; Morris, Amanda Jean Patent: US2013/303531 A1, 2013 ; Location in patent: Paragraph 0107; 0111; 0112 ;

110-89-4 109-70-6 ~65% 1458-63-5

文献：Buchanan, John L.; Newcomb, John R.; Carney, David P.; Chaffee, Stuart C.; Chai, Lilly; Cupples, Rod; Epstein, Linda F.; Gallant, Paul; Gu, Yan; Harmange, Jean-Christophe; Hodge, Kathy; Houk, Brett E.; Huang, Xin; Jona, Janan; Joseph, Smriti; Jun, H. Toni; Kumar, Rakesh; Li, Chun; Lu, John; Menges, Tom; Morrison, Michael J.; Novak, Perry M.; Van Der Plas, Simon; Radinsky, Robert; Rose, Paul E.; Sawant, Satin; Sun, Ji-Rong; Surapaneni, Sekhar; Turci, Susan M.; Xu, Keyang; Yanez, Evelyn; Zhao, Huilin; Zhu, Xiaotian Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 8 p. 2394 - 2399

104-58-5 ~90% 1458-63-5

文献：Le Sann, Christine; Huddleston, Jonathan; Mann, John Tetrahedron, 2007 , vol. 63, # 52 p. 12903 - 12911

19653-33-9 ~% 1458-63-5

文献：Magidson; Strukow Zhurnal Obshchei Khimii, 1934 , vol. 4, p. 253,266 Archiv der Pharmazie (Weinheim, Germany), 1933 , vol. 271, p. 569,579 Chem. Zentralbl., 1935 , vol. 106, # I p. 2984

海关

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%