380917-97-5

• 常用中文名：吡仑帕奈
• 常用英文名：Perampanel
• CAS号：380917-97-5
• 分子式：C₂₃H₁₅N₃O
• 分子量：349.385
• 发布时间：2018-04-01 08:00:00
• 更新时间：2024-01-02 23:02:42
• Perampanel(E2007; ER 155055-90) is a selective noncompetitive AMPA-type glutamate receptor antagonist which has demonstrated anticonvulsant activity in experimental seizure models and antiepileptic activity in clinical trials.

名称

• 中文名: 吡仑帕奈
• 英文名: perampanel
• 英文别名: 2-(6'-Oxo-1'-phenyl-1',6'-dihydro-2,3'-bipyridin-5'-yl)benzonitrile; E-2007; Perampanel; 3-(2-Cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-one; 5'-(2-cyanophenyl)-1'-phenyl-2,3'-bipyridinyl-6'(1'H)-one; 2-(2-oxo-1-phenyl-5-pyridin-2-ylpyridin-3-yl)benzonitrile; Fycompa; [14C]-Perampanel; 2-[1',6'-dihydro-6'-oxo-1-phenyl-(2',3'-bipyridin)-5'-yl]benzonitrile; Benzonitrile, 2-(1',6'-dihydro-6'-oxo-1'-phenyl[2,3'-bipyridin]-5'-yl)-

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 619.1±55.0 °C at 760 mmHg
• 分子式: C₂₃H₁₅N₃O
• 分子量: 349.385
• 闪点: 328.2±31.5 °C
• 精确质量: 349.121521
• PSA: 58.68000
• LogP: 3.70
• 外观性状: 白色固体
• 蒸汽压: 0.0±1.8 mmHg at 25°C
• 折射率: 1.706
• 储存条件: 室温，干燥，密封

安全

• 危害码 (欧洲): Xi

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