254751-08-1

• 常用中文名：2-((2-(叔丁基)苯基)氨基)-2-氧代乙酸
• 常用英文名：Acetic acid, 2-[[2-(1,1-dimethylethyl)phenyl]amino]-2-oxo
• CAS号：254751-08-1
• 分子式：C₁₂H₁₅NO₃
• 分子量：221.25200
• 发布时间：2016-11-16 09:37:07
• 更新时间：2026-07-06 22:09:58

名称

• 中文名: 2-((2-(叔丁基)苯基)氨基)-2-氧代乙酸
• 英文名: {[2-(2-Methyl-2-propanyl)phenyl]amino}(oxo)acetic acid
• 中文别名: EMRICASAN254750-的中间体; 2 - ((2-(叔丁基)苯基)氨基)-2-氧代乙酸
• 英文别名: N-(2-tert-butylphenylamino)oxamic acid; N-(2-tert-butylphenyl)oxamic acid; 2-((2-(Tert-butyl)phenyl)amino)-2-oxoacetic acid; Emricasan int; Acetamide,N-[2-(1,1-dimethylethyl)phenyl]-N-methyl; 2-t-butylphenyloxamic acid; Acetic acid, 2-[[2-(1,1-diMethylethyl)phenyl]amino]-2-oxo; Essigsaeure-(2-tert-butyl-N-methyl-anilid); acetic acid-(2-tert-butyl-N-methyl-anilide); rac-N-(2-tert-butylphenyl)-N-methyl acetamide

物化性质

• 分子式: C₁₂H₁₅NO₃
• 分子量: 221.25200
• 精确质量: 221.10500
• PSA: 66.40000
• LogP: 2.08020
• 储存条件: 室温

合成路线

483334-60-7 ~58% 254751-08-1

文献：Linton, Steven D.; Aja, Teresa; Armstrong, Robert A.; Bai, Xu; Chen, Long-Shiuh; Chen, Ning; Ching, Brett; Contreras, Patricia; Diaz, Jose-Luis; Fisher, Craig D.; Fritz, Lawrence C.; Gladstone, Patricia; Groessl, Todd; Gu, Xin; Herrmann, Julia; Hirakawa, Brad P.; Hoglen, Niel C.; Jahangiri, Kathy G.; Kalish, Vincent J.; Karanewsky, Donald S.; Kodandapani, Lalitha; Krebs, Joseph; McQuiston, Jeff; Meduna, Steven P.; Nalley, Kip; Robinson, Edward D.; Sayers, Robert O.; Sebring, Kristen; Spada, Alfred P.; Ternansky, Robert J.; Tomaselli, Kevin J.; Ullman, Brett R.; Valentino, Karen L.; Weeks, Suzanne; Winn, David; Wu, Joe C.; Yeo, Pauline; Zhang, Cheng-Zhi Journal of Medicinal Chemistry, 2005 , vol. 48, # 22 p. 6779 - 6782

6310-21-0 ~% 254751-08-1

文献：Linton, Steven D.; Aja, Teresa; Allegrini, Peter R.; Deckwerth, Thomas L.; Diaz, Jose-Luis; Hengerer, Bastian; Herrmann, Julia; Jahangiri, Kathy G.; Kallen, Joerg; Karanewsky, Donald S.; Meduna, Steven P.; Nalley, Kip; Robinson, Edward D.; Roggo, Silvio; Rovelli, Giorgio; Sauter, Andre; Sayers, Robert O.; Schmitz, Albert; Smidt, Robert; Ternansky, Robert J.; Tomaselli, Kevin J.; Ullman, Brett R.; Wiessner, Christoph; Wu, Joe C. Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 10 p. 2685 - 2691

上下游产品

上游产品  2
483334-60-7 6310-21-0
下游产品  1
254750-83-9