864082-26-8

• 常用中文名：1,4,5,6-四氢-2-甲基-6-氧代-4-[4-(氟)苯基]-3-吡啶羧酸
• 常用英文名：1,4,5,6-TETRAHYDRO-2-METHYL-6-OXO-4-[4-(FLUORO)PHENYL]-3-PYRIDINECARBOXYLIC ACID
• CAS号：864082-26-8
• 分子式：C₁₃H₁₂FNO₃
• 分子量：249.23800
• 发布时间：2018-10-16 10:42:29
• 更新时间：2024-04-02 10:41:22

名称

• 中文名: 1,4,5,6-四氢-2-甲基-6-氧代-4-[4-(氟)苯基]-3-吡啶羧酸
• 英文名: 4-(4-fluorophenyl)-6-methyl-2-oxo-3,4-dihydro-1H-pyridine-5-carboxylic acid
• 英文别名: 3-Pyridinecarboxylicacid,4-(4-fluorophenyl)-1,4,5,6-tetrahydro-2-methyl-6-oxo; 4-(4-fluorophenyl)-2-methyl-6-oxo-1,4,5,6-tetrahydro-3-pyridinecarboxylic acid; 1,4,5,6-Tetrahydro-2-methyl-6-oxo-4-[4-(fluoro)phenyl]-3-pyridinecarboxylicacid

物化性质

• 分子式: C₁₃H₁₂FNO₃
• 分子量: 249.23800
• 精确质量: 249.08000
• PSA: 69.89000
• LogP: 2.06370

合成路线

299207-90-2 ~64% 864082-26-8

文献：SMITHKLINE BEECHAM CORPORATION Patent: WO2005/82890 A1, 2005 ; Location in patent: Page/Page column 26 ; WO 2005/082890 A1

459-57-4 ~% 864082-26-8

文献：Goodman, Krista B.; Cui, Haifeng; Dowdell, Sarah E.; Gaitanopoulos, Dimitri E.; Ivy, Robert L.; Sehon, Clark A.; Stavenger, Robert A.; Wang, Gren Z.; Viet, Andrew Q.; Xu, Weiwei; Ye, Guosen; Semus, Simon F.; Evans, Christopher; Fries, Harvey E.; Jolivette, Larry J.; Kirkpatrick, Robert B.; Dul, Edward; Khandekar, Sanjay S.; Yi, Tracey; Jung, David K.; Wright, Lois L.; Smith, Gary K.; Behm, David J.; Bentley, Ross; Doe, Christopher P.; Hu, Erding; Lee, Dennis Journal of Medicinal Chemistry, 2007 , vol. 50, # 1 p. 6 - 9

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