1175273-62-7

• 常用中文名：1-(4-哌啶基)-1H-吡唑-4-硼酸频那醇盐酸盐
• 常用英文名：4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazol-1-yl]piperidine,hydrochloride
• CAS号：1175273-62-7
• 分子式：C₁₄H₂₅BClN₃O₂
• 分子量：313.63100
• 发布时间：2018-10-21 17:03:08
• 更新时间：2026-09-11 05:57:27

名称

• 中文名: 1-(4-哌啶基)-1H-吡唑-4-硼酸频那醇盐酸盐
• 英文名: 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazol-1-yl]piperidine,hydrochloride
• 中文别名: 4-(4-(4,4,5,5-四甲基-1,3,2-二氧硼杂环戊烷-2-基)-1H-吡唑-1-基)哌啶盐酸盐
• 英文别名: 1-(4-Piperidinyl)-1h-pyrazole-4-boronic acid, pinacol este, HCl; 1-(Piperidin-4-yl)-1H-pyrazole-4-boronic acid, pinacol ester hydrochloride; 4-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine hydrochloride, 1-(Piperidin-4-yl)-4-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole hydrochloride; 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazol-1-yl]piperidine; 4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)piperidine hydrochloride

物化性质

• 分子式: C₁₄H₂₅BClN₃O₂
• 分子量: 313.63100
• 精确质量: 313.17300
• PSA: 48.31000
• LogP: 2.23760

合成路线

877399-74-1 ~99% 1175273-62-7

文献：OSI PHARMACEUTICALS, LLC; HOMBERGER, Keith, R.; BERGER, Dan, M.; CHEN, Xin; CREW, Andrew, P.; DONG, Hanqing; KLEINBERG, Andrew; LI, An-Hu; MA, Lifu; MULVIHILL, Mark, J.; PANICKER, Bijoy; SIU, Kam, W.; STEINIG, Arno, G.; TARRANT, James, G.; WANG, Jing; WENG, Qinghua; SANGEM, Rajaram; GUPTA, Ramesh, C. Patent: WO2011/100502 A1, 2011 ; Location in patent: Page/Page column 42 ; WO 2011/100502 A1

109384-19-2 ~% 1175273-62-7

文献：HUTCHISON MEDIPHARMA LIMITED; Su, Wei-Guo; Deng, Wei; Ji, Jianguo Patent: US2014/121200 A1, 2014 ;

141699-59-4 ~% 1175273-62-7

文献：HUTCHISON MEDIPHARMA LIMITED; Su, Wei-Guo; Deng, Wei; Ji, Jianguo Patent: US2014/121200 A1, 2014 ;

269410-08-4 ~% 1175273-62-7

文献：OSI PHARMACEUTICALS, LLC; LI, An-Hu; MULVIHILL, Mark, J.; STEINIG, Arno, G. Patent: WO2011/143646 A1, 2011 ; WO 2011/143646 A1