71074-49-2

• 常用中文名：甲氨蝶呤IMPM
• 常用英文名：L-Glutamic acid,N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-a-glutamyl- (9CI)
• CAS号：71074-49-2
• 分子式：C₂₅H₂₉N₉O₈
• 分子量：583.55300
• 发布时间：2016-09-30 18:52:23
• 更新时间：2026-07-16 13:25:42

名称

• 中文名: 甲氨蝶呤IMPM
• 英文名: 2-[[4-carboxy-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]butanoyl]amino]pentanedioic acid
• 英文别名: ((S)-4-cboxy-4-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)butanoyl)-L-glutamic acid; 2-[[2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]-5-hydroxy-5-oxopentanoyl]amino]pentanedioic acid; methotrexate-alpha glutamate; Methotrexatealpha glutamate,Methotrexate alpha glutamate; L-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-α-glutamyl- (9CI); Meapa-glu-glu

物化性质

• 密度: 1.539g/cm3
• 分子式: C₂₅H₂₉N₉O₈
• 分子量: 583.55300
• 精确质量: 583.21400
• PSA: 276.94000
• LogP: 1.56220
• 折射率: 1.704

合成路线

1676-73-9 ~% 71074-49-2

文献：Piper; Montgomery; Sirotnak; Chello Journal of Medicinal Chemistry, 1982 , vol. 25, # 2 p. 182 - 187

10541-83-0 ~% 71074-49-2

文献：Piper; Montgomery; Sirotnak; Chello Journal of Medicinal Chemistry, 1982 , vol. 25, # 2 p. 182 - 187

2528-30-5 ~% 71074-49-2

文献：Piper; Montgomery; Sirotnak; Chello Journal of Medicinal Chemistry, 1982 , vol. 25, # 2 p. 182 - 187

66891-86-9 ~% 71074-49-2

文献：Piper; Montgomery; Sirotnak; Chello Journal of Medicinal Chemistry, 1982 , vol. 25, # 2 p. 182 - 187

79974-22-4 ~% 71074-49-2

文献：Piper; Montgomery; Sirotnak; Chello Journal of Medicinal Chemistry, 1982 , vol. 25, # 2 p. 182 - 187

79974-13-3 ~% 71074-49-2

文献：Piper; Montgomery; Sirotnak; Chello Journal of Medicinal Chemistry, 1982 , vol. 25, # 2 p. 182 - 187

上下游产品

上游产品  6
1676-73-9 10541-83-0 2528-30-5 66891-86-9
79974-22-4 79974-13-3
下游产品  0