121021-51-0

• 常用中文名：依西美坦杂质
• 常用英文名：6β-Hydroxymethylandrosta-1,4-diene-3,17-dione
• CAS号：121021-51-0
• 分子式：C₂₀H₂₆O₃
• 分子量：314.419
• 发布时间：2018-09-19 14:12:52
• 更新时间：2026-07-06 10:52:07

名称

• 中文名: 依西美坦杂质
• 英文名: 6β-Hydroxymethylandrosta-1,4-diene-3,17-dione
• 中文别名: 依西美坦杂质47; 依西美坦相关化合物2; 依西美坦杂质B 标准品; (6R,8R,9S,10R,13S,14S)-6-(羟甲基)-10,13-二甲基-7,8,9,10,11,12,13,14,15,16-十氢-3H-环戊[A]菲-3,17(6H)-二酮; 依西美坦相关物质B; 依西美坦片杂质a; 依西美坦杂质B; 依西美坦杂质B AS 6Β-异构体; 6BETA-(羟基甲基)雄甾-1,4-二烯-3,17-二酮; 依西美坦杂质B(6Β-异构体); 6-Β-依西美坦 杂质 B(6-Β-依西美坦 相关化合物 B)
• 英文别名: Exemestane Tablets Impurity a; 6-beta-Exemestane Impurity B (6-beta-Exemestane Related Compound B); 6β-(HydroxyMethyl)androsta-1,4-dien-3,17-dione; Exemestane Related Compound B; Valine Impurity 51; 6beta-(Hydroxymethyl)androsta-1,4-dien-3,17-dione; Exemestane 6β-Hydroxymethylandrosta-1,4-diene-3,17-dione; Exemestane Impurity B as 6β-Isomer; (6β)-6-(Hydroxymethyl)androsta-1,4-diene-3,17-dione; Exemestane Related Compound B (15 mg) (6-hydroxymethylandrostra-1,4-diene-3,17-dione); 6beta-Hydroxymethylandrosta-1,4-diene-3,17-dione; CID145714482; (6R,8R,9S,10R,13S,14S)-6-(Hydroxymethyl)-10,13-dimethyl-7,8,9,10,11,12,13,14,15,16-decahydro-3H-cyclopenta[a]phenanthrene-3,17(6H)-dione; (6R,8R,9S,10R,13S,14S)-6-(hydroxymethyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-dione; Androsta-1,4-diene-3,17-dione, 6-(hydroxymethyl)-, (6β)

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 492.0±45.0 °C at 760 mmHg
• 分子式: C₂₀H₂₆O₃
• 分子量: 314.419
• 闪点: 265.4±25.2 °C
• 精确质量: 314.188202
• PSA: 54.37000
• LogP: 1.63
• 蒸汽压: 0.0±2.8 mmHg at 25°C
• 折射率: 1.581

合成路线

50-00-0 67737-88-6 ~% 121021-51-0

文献：Goelitzer; Bonnekessel; Jones; Palusczak; Hartmann Pharmazie, 2006 , vol. 61, # 7 p. 575 - 581

897-06-3 ~% 121021-51-0

文献：Buzzetti; Di Salle; Longo; Briatico Steroids, 1993 , vol. 58, # 11 p. 527 - 532

上下游产品

上游产品  3
50-00-0 67737-88-6 897-06-3
下游产品  0