221246-34-0

• 常用中文名：17-TRIFLUOROMETHYLPHENYL TRINOR PROSTAGLANDIN F2ALPHA
• 常用英文名：17-TRIFLUOROMETHYLPHENYL TRINOR PROSTAGLANDIN F2ALPHA
• CAS号：221246-34-0
• 分子式：C₂₄H₃₁F₃O₅
• 分子量：456.495
• 发布时间：2016-10-29 00:10:00
• 更新时间：2024-01-09 13:42:28
• 17-trifluoromethylphenyl trinor Prostaglandin F2α bears an aromatic ring, and acts very much like the free acid of travoprost.

名称

• 英文名: (1R,2S,3R)-3-ethyl-2-[(3S)-3-hydroxy-5-[3-(trifluoromethyl)phenyl]pent-1-enyl]cyclopentan-1-ol
• 英文别名: (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-{(1E,3S)-3-hydroxy-5-[3-(trifluoromethyl)phenyl]-1-penten-1-yl}cyclopentyl]-5-heptenoic acid; 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-[3-(trifluoromethyl)phenyl]-1-penten-1-yl]cyclopentyl]-, (5Z)-; (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-{(1E,3S)-3-hydroxy-5-[3-(trifluoromethyl)phenyl]pent-1-en-1-yl}cyclopentyl]hept-5-enoic acid; (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-{(1E,3S)-3-hydroxy-5-[4-(trifluoromethyl)phenyl]-1-penten-1-yl}cyclopentyl]-5-heptenoic acid; 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-[4-(trifluoromethyl)phenyl]-1-penten-1-yl]cyclopentyl]-, (5Z)-; 17-trifluoromethylphenyl trinor Prostaglandin F2alpha

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 600.0±50.0 °C at 760 mmHg
• 分子式: C₂₄H₃₁F₃O₅
• 分子量: 456.495
• 闪点: 316.6±30.1 °C
• 精确质量: 456.212372
• PSA: 97.99000
• LogP: 2.69
• 蒸汽压: 0.0±1.8 mmHg at 25°C
• 折射率: 1.575
• 储存条件: -20°C，密闭，干燥

合成路线

779-89-5 ~% 221246-34-0

文献：DeLong, Mitchell A.; Amburgey, Jack; Taylor, Cynthia; Wos, John A.; Soper, David L.; Wang, Yili; Hicks, Renee Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 14 p. 1519 - 1522

294856-07-8 ~% 221246-34-0

文献：DeLong, Mitchell A.; Amburgey, Jack; Taylor, Cynthia; Wos, John A.; Soper, David L.; Wang, Yili; Hicks, Renee Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 14 p. 1519 - 1522

70783-99-2 ~% 221246-34-0

文献：DeLong, Mitchell A.; Amburgey, Jack; Taylor, Cynthia; Wos, John A.; Soper, David L.; Wang, Yili; Hicks, Renee Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 14 p. 1519 - 1522

585-50-2 ~% 221246-34-0

文献：DeLong, Mitchell A.; Amburgey, Jack; Taylor, Cynthia; Wos, John A.; Soper, David L.; Wang, Yili; Hicks, Renee Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 14 p. 1519 - 1522

294856-02-3 ~% 221246-34-0

文献：DeLong, Mitchell A.; Amburgey, Jack; Taylor, Cynthia; Wos, John A.; Soper, David L.; Wang, Yili; Hicks, Renee Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 14 p. 1519 - 1522

294856-05-6 ~% 221246-34-0

文献：DeLong, Mitchell A.; Amburgey, Jack; Taylor, Cynthia; Wos, John A.; Soper, David L.; Wang, Yili; Hicks, Renee Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 14 p. 1519 - 1522

294856-03-4 ~% 221246-34-0

文献：DeLong, Mitchell A.; Amburgey, Jack; Taylor, Cynthia; Wos, John A.; Soper, David L.; Wang, Yili; Hicks, Renee Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 14 p. 1519 - 1522

294856-04-5 ~% 221246-34-0

文献：DeLong, Mitchell A.; Amburgey, Jack; Taylor, Cynthia; Wos, John A.; Soper, David L.; Wang, Yili; Hicks, Renee Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 14 p. 1519 - 1522

294856-06-7 ~% 221246-34-0

文献：DeLong, Mitchell A.; Amburgey, Jack; Taylor, Cynthia; Wos, John A.; Soper, David L.; Wang, Yili; Hicks, Renee Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 14 p. 1519 - 1522

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