261380-31-8

• 常用中文名：(R)-2-((叔-丁氧羰基)氨基)-3-(2,5-二氟苯基)丙酸
• 常用英文名：(2R)-(+)-1-AMINO-3-PHENOXY-2-PROPANOL
• CAS号：261380-31-8
• 分子式：C₁₄H₁₇F₂NO₄
• 分子量：301.28600
• 发布时间：2018-08-28 19:12:38
• 更新时间：2024-01-08 23:20:09

名称

• 中文名: (2R)-2-[(叔丁氧基羰基)氨基]-3-(2,5-二氟苯基)丙酸
• 英文名: (2R)-3-(2,5-difluorophenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid
• 英文别名: Boc-2,5-difluoro-D-phenylalanine; N-Boc-2,5-difluoro-D-phenylalanine

物化性质

• 密度: 1.27g/cm3
• 沸点: 424.5ºC at 760 mmHg
• 分子式: C₁₄H₁₇F₂NO₄
• 分子量: 301.28600
• 闪点: 210.6ºC
• 精确质量: 301.11300
• PSA: 75.63000
• LogP: 2.87610
• 蒸汽压: 5.77E-08mmHg at 25°C
• 折射率: 1.506
• 储存条件: 2-8°C， 密封， 干燥

合成路线

837430-11-2 ~% 261380-31-8

文献：Yu, Hannah; Richey, Rachel N.; Stout, James R.; LaPack, Mark A.; Gu, Ruilin; Khau, Vien V.; Frank, Scott A.; Ott, Joel P.; Miller, Richard D.; Carr, Michael A.; Zhang, Tony Y. Organic Process Research and Development, 2008 , vol. 12, # 2 p. 218 - 225

24424-99-5 ~% 261380-31-8

文献：Kim, Dooseop; Wang, Liping; Beconi, Maria; Eiermann, George J.; Fisher, Michael H.; He, Huaibing; Hickey, Gerard J.; Kowalchick, Jennifer E.; Leiting, Barbara; Lyons, Kathryn; Marsilio, Frank; McCann, Margaret E.; Patel, Reshma A.; Petrov, Aleksandr; Scapin, Giovanna; Patel, Sangita B.; Roy, Ranabir Sinha; Wu, Joseph K.; Wyvratt, Matthew J.; Zhang, Bei B.; Zhu, Lan; Thornberry, Nancy A.; Weber, Ann E. Journal of Medicinal Chemistry, 2005 , vol. 48, # 1 p. 141 - 151

85117-99-3 ~% 261380-31-8

文献：Kim, Dooseop; Wang, Liping; Beconi, Maria; Eiermann, George J.; Fisher, Michael H.; He, Huaibing; Hickey, Gerard J.; Kowalchick, Jennifer E.; Leiting, Barbara; Lyons, Kathryn; Marsilio, Frank; McCann, Margaret E.; Patel, Reshma A.; Petrov, Aleksandr; Scapin, Giovanna; Patel, Sangita B.; Roy, Ranabir Sinha; Wu, Joseph K.; Wyvratt, Matthew J.; Zhang, Bei B.; Zhu, Lan; Thornberry, Nancy A.; Weber, Ann E. Journal of Medicinal Chemistry, 2005 , vol. 48, # 1 p. 141 - 151

837430-10-1 ~% 261380-31-8

文献：Kim, Dooseop; Wang, Liping; Beconi, Maria; Eiermann, George J.; Fisher, Michael H.; He, Huaibing; Hickey, Gerard J.; Kowalchick, Jennifer E.; Leiting, Barbara; Lyons, Kathryn; Marsilio, Frank; McCann, Margaret E.; Patel, Reshma A.; Petrov, Aleksandr; Scapin, Giovanna; Patel, Sangita B.; Roy, Ranabir Sinha; Wu, Joseph K.; Wyvratt, Matthew J.; Zhang, Bei B.; Zhu, Lan; Thornberry, Nancy A.; Weber, Ann E. Journal of Medicinal Chemistry, 2005 , vol. 48, # 1 p. 141 - 151