CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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HM3657000
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CHEMICAL NAME :
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1H-1,3-Diazepine-4-carboxylic acid, hexahydro-2-imino-, isopropyl ester, monohydrochloride, (-)-
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CAS REGISTRY NUMBER :
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26281-64-1
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LAST UPDATED :
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199112
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DATA ITEMS CITED :
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3
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MOLECULAR FORMULA :
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C9-H17-N3-O2.Cl-H
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MOLECULAR WEIGHT :
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235.75
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WISWESSER LINE NOTATION :
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T7MYMTJ BUM DVOY1&1 &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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450 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 185,159,1970
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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42 mg/kg
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TOXIC EFFECTS :
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Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Autonomic Nervous System - ganglion facilitant
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REFERENCE :
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AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 189,408,1971
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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6200 ug/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 185,159,1970
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