6098-44-8

• 常用中文名：Acetamide,N-(acetyloxy)-N-9H-fluoren-2-yl-
• 常用英文名：Acetamide,N-(acetyloxy)-N-9H-fluoren-2-yl-
• CAS号：6098-44-8
• 分子式：C₁₇H₁₅NO₃
• 分子量：281.30600
• 发布时间：2017-02-01 06:59:28
• 更新时间：2024-01-09 13:46:59

名称

• 英文名: N-acetoxy-2-acetamidofluorene
• 英文别名: N-Acetoxy-2-fluorenylacetamide; [acetyl(9H-fluoren-2-yl)amino] acetate; 2-Acetoxyacetylaminofluorene; 2-acetoxy-2-acetylaminofluorene; N-Acetoxy-N-2-fluorenylacetamide; N-Acetoxy-N-acetyl-2-aminofluorene; N-Acetoxy-2-acetamidofluorene; ACETOXYACETYLAMINOFLUORENE; Acetoxyacetamidofluorene; Acetoxy AAF; NAAAF

物化性质

• 密度: 1.279g/cm3
• 沸点: 445.1ºC at 760 mmHg
• 分子式: C₁₇H₁₅NO₃
• 分子量: 281.30600
• 闪点: 223ºC
• 精确质量: 281.10500
• PSA: 46.61000
• LogP: 3.08880
• 折射率: 1.639
• 储存条件: 库房通风低温干燥

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : NC3420000 CHEMICAL NAME : Hydroxylamine, N,O-diacetyl-N-fluoren-2-yl- CAS REGISTRY NUMBER : 6098-44-8 LAST UPDATED : 199806 DATA ITEMS CITED : 110 MOLECULAR FORMULA : C17-H15-N-O3 MOLECULAR WEIGHT : 281.33 WISWESSER LINE NOTATION : L B656 HHJ ENV1&OV1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >660 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 21 mg/kg TOXIC EFFECTS : Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Implant SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 28 mg/kg TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors TYPE OF TEST : Specific locus test TYPE OF TEST : Cytogenetic analysis TYPE OF TEST : Sex chromosome loss and nondisjunction TYPE OF TEST : Cytogenetic analysis TYPE OF TEST : DNA damage TYPE OF TEST : DNA damage TYPE OF TEST : Sister chromatid exchange TYPE OF TEST : DNA adduct MUTATION DATA TYPE OF TEST : DNA adduct TEST SYSTEM : Mammal - species unspecified Lymphocyte DOSE/DURATION : 136 mmol/L REFERENCE : CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 3,81,1982

合成路线

53-95-2 108-24-7 ~82% 6098-44-8

文献：Elfarra; Hanna Journal of Medicinal Chemistry, 1985 , vol. 28, # 10 p. 1453 - 1460

607-57-8 108-24-7 ~81% 6098-44-8 53-96-3

文献：Kim, Byeong Hyo; Jun, Young Moo; Suh, Seung Won; Baik, Woonphil; Lee, Byung Min Journal of Chemical Research - Part S, 1998 , # 1 p. 46 - 47

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