82608-05-7

• 常用中文名：2-Benzoxazolinone, 3-methyl-6-((4-(alpha,alpha,alpha-trifluoro-m-tolyl)-4-piperazinyl)acetyl)-
• 常用英文名：2-Benzoxazolinone, 3-methyl-6-((4-(alpha,alpha,alpha-trifluoro-m-tolyl)-4-piperazinyl)acetyl)-
• CAS号：82608-05-7
• 分子式：C₂₁H₂₀F₃N₃O₃
• 分子量：419.39700
• 发布时间：2016-10-26 10:27:53
• 更新时间：2024-01-18 07:55:10

名称

• 英文名: 3-methyl-6-[2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]acetyl]-1,3-benzoxazol-2-one
• 英文别名: 6-<4-(3-trifluoromethylphenyl)-1-piperazinyl>acetyl-3-methyl benzoxazolinone; 2(3H)-Benzoxalzolone,3-methyl-6-((4-(3-(trifluoromethyl)phenyl)-1-piperazinyl)acetyl)

物化性质

• 密度: 1.348g/cm3
• 沸点: 552.6ºC at 760 mmHg
• 分子式: C₂₁H₂₀F₃N₃O₃
• 分子量: 419.39700
• 闪点: 288ºC
• 精确质量: 419.14600
• PSA: 58.69000
• LogP: 3.15810
• 折射率: 1.571

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DM5276530 CHEMICAL NAME : 2-Benzoxazolinone, 3-methyl-6-((4-(alpha,alpha,alpha-trifluoro-m-tolyl)- 4-piperazinyl) acetyl)- CAS REGISTRY NUMBER : 82608-05-7 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C21-H20-F3-N3-O3 MOLECULAR WEIGHT : 419.44 WISWESSER LINE NOTATION : T56 BNVOJ B1 GV1- AT6N DNTJ DR CXFFF HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 32,604,1982

合成路线

79851-85-7 15532-75-9 ~76% 82608-05-7

文献：Bermann; Berthelot; Bonte; Debaert; Lesieur; Brunet; Cazin; Luyckx Arzneimittel-Forschung/Drug Research, 1982 , vol. 32, # 6 p. 604 - 610

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