92264-45-4

• 常用中文名：N-(Trifluoroacetyl)thiodemecolcine
• 常用英文名：N-(Trifluoroacetyl)thiodemecolcine
• CAS号：92264-45-4
• 分子式：C₂₃H₂₄F₃NO₅S
• 分子量：483.50100
• 发布时间：2017-08-19 08:56:56
• 更新时间：2024-04-04 22:46:51

名称

• 英文名: Acetamide, 2,2,2-trifluoro-N-methyl-N-[5,6,7,9-tetrahydro-1,2,3-trimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]-, (S)
• 英文别名: Faveptv; L-Valine,N-(O-(oxiranylmethyl)-N-(N-(trifluoroacetyl)-L-valyl)-L-tyrosyl)-,methyl ester; N-(trifluoroacetyl)thiodemecolcine; N-(Trifluoroacetyl)-val-O'-(2,3-epoxypropyl)-tyr-val methyl ester; N-(Trifluoroacetyl)valyl-O'-(2,3-epoxypropyl)tyrosyl-valine methyl ester; N-(trifluoroacetyl)-L-valyl-O'-(2,3-epoxypropyl)-L-tyrosyl-L-valine methyl ester

物化性质

• 密度: 1.35g/cm3
• 沸点: 697.6ºC at 760 mmHg
• 分子式: C₂₃H₂₄F₃NO₅S
• 分子量: 483.50100
• 闪点: 375.7ºC
• 精确质量: 483.13300
• PSA: 90.37000
• LogP: 4.46950
• 折射率: 1.577

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : AC6149500 CHEMICAL NAME : Acetamide, N-methyl-N-(10-(methylthio)-9-oxo-1,2,3-trimethoxy-5, 6,7,9-tetrahydrobenzo (a) heptalen-7-yl)-2,2,2-trifluoro- CAS REGISTRY NUMBER : 92264-45-4 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C23-H24-F3-N-O5-S MOLECULAR WEIGHT : 483.54 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 18600 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 28,1204,1985

合成路线

76129-16-3 74-88-4 ~87% 92264-45-4

文献：Kerekes, Peter; Sharma, Padam N.; Brossi, Arnold; Chignell, Colin F.; Quinn, Frank R. Journal of Medicinal Chemistry, 1985 , vol. 28, # 9 p. 1204 - 1208

2731-16-0 ~% 92264-45-4

文献：Kerekes, Peter; Sharma, Padam N.; Brossi, Arnold; Chignell, Colin F.; Quinn, Frank R. Journal of Medicinal Chemistry, 1985 , vol. 28, # 9 p. 1204 - 1208

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