22246-05-5

• 常用中文名：3,4-二氢-7-羟基-1(2H)-异喹啉酮
• 常用英文名：7-Hydroxy-3,4-dihydro-1(2H)-isoquinolinone
• CAS号：22246-05-5
• 分子式：C₉H₉NO₂
• 分子量：163.173
• 发布时间：2018-12-31 07:42:55
• 更新时间：2024-01-23 20:09:26

名称

• 中文名: 7-羟基-3,4-二氢-2H-异喹啉-1-酮
• 英文名: 7-hydroxy-3,4-dihydro-2h-isoquinolin-1-one
• 中文别名: 3,4-二氢-7-羟基-1(2H)-异喹啉酮
• 英文别名: 1(2H)-Isoquinolinone, 3,4-dihydro-7-hydroxy-; 3,4-Dihydro-7-hydroxy-1(2H)-isoquinolinone; 7-hydroxy-3,4-dihydro-1-oxo-2(1H)-isoquinoline; ISO068; 7-Hydroxy-3,4-dihydro-1(2H)-isoquinolinone; 7-Hydroxy-3,4-dihydro-2H-isochinolinon-(1); 7-hydroxy-3,4-dihydroisoquinolin-1(2H)-one; 1(2H)-Isoquinolinone,3,4-dihydro-7-hydroxy

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 500.4±50.0 °C at 760 mmHg
• 分子式: C₉H₉NO₂
• 分子量: 163.173
• 闪点: 256.5±30.1 °C
• 精确质量: 163.063324
• PSA: 49.33000
• LogP: 0.05
• 蒸汽压: 0.0±1.3 mmHg at 25°C
• 折射率: 1.604
• 储存条件: 室温，保存在惰性气体中

合成路线

22246-04-4 ~95% 22246-05-5

文献：Fisher, Matthew J.; Gunn, Bruce; Harms, Cathy S.; Kline, Allen D.; Mullaney, Jeffrey T.; Nunes, Anne; Scarborough, Robert M.; Arfsten, Ann E.; Skelton, Marshall A.; Um, Suzane L.; Utterback, Barbara G.; Jakubowski, Joseph A. Journal of Medicinal Chemistry, 1997 , vol. 40, # 13 p. 2085 - 2101

91247-71-1 ~79% 22246-05-5

文献：Kurouchi, Hiroaki; Kawamoto, Kyoko; Sugimoto, Hiromichi; Nakamura, Satoshi; Otani, Yuko; Ohwada, Tomohiko Journal of Organic Chemistry, 2012 , vol. 77, # 20 p. 9313 - 9328,16

62372-08-1 ~83% 22246-05-5

文献：Kurouchi, Hiroaki; Kawamoto, Kyoko; Sugimoto, Hiromichi; Nakamura, Satoshi; Otani, Yuko; Ohwada, Tomohiko Journal of Organic Chemistry, 2012 , vol. 77, # 20 p. 9313 - 9328,16

55-81-2 ~% 22246-05-5

文献：Journal of Organic Chemistry, , vol. 77, # 20 p. 9313 - 9328,16

13623-25-1 ~% 22246-05-5

文献：WO2012/3418 A2, ; WO 2012/003418 A2

上下游产品

上游产品  5
22246-04-4 91247-71-1 62372-08-1 55-81-2
13623-25-1
下游产品  2
190604-11-6 917884-95-8