13649-88-2

• 常用中文名：地夫可特
• 常用英文名：Deflazacort intermediate
• CAS号：13649-88-2
• 分子式：C₂₃H₂₉NO₄
• 分子量：383.481
• 相关类别： 原料药 激素及调节内分泌功能类药 肾上腺皮质激素类药
• 发布时间：2018-04-15 08:00:00
• 更新时间：2026-07-03 18:48:40

名称

• 中文名: 地夫可特
• 英文名: 21-Deacetoxy Deflazacort
• 中文别名: 地夫可特中间体(D8); D5,地那查可特; 21-脱乙酰氧基地夫可特; (11B,16B)-11-羟基-2'-甲基-5'H-孕甾-1,4-二烯并[17,16d]异恶唑-3,20-二酮; 脱乙酰氧基地夫可特; 中间体(D5); 21-去乙酰地夫可特; 地夫可特脱乙酰氧; 地夫可特杂质20; 地夫可特|地那查可特|13-2
• 英文别名: Deflazacort Intermediate (D5); 21-Desacetoxydeflazacort; (11β,16β)-11-hydroxy-2'-Methyl-5'H-Pregna-1,4-dieno[17,16-d]oxazole-3,20-dione; (6,6bS,7S,8aS,8bS,11,12aS,12bS); 5′βH-Pregna-1,4-dieno[17,16-d]oxazole-3,20-dione,11β-hydroxy-2′-methyl; (6,6bS,7S,8aS,8bS,11,12aS,12bS)-8b-Acetyl-7-hydroxy-6a,8a,10-trimethyl-6a,6b,7,8,8a,8b,11a,12,12a,12b-decahydro-1H-naphtho[2',1':4,5]indeno[1,2-d]oxazol-4(2H)-one; deflazacort; 11β-hydroxy-2'-methyl-5'βh-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione; Desacetoxy Deflazacort; βH-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione; Deflazacort Intermediates(D5); Deflazacort intermediates; (4,4BS,5S,6AS,9,10AS,10BS)-6B-ACETYL-5-HYDROXY-4A,6A,8-TRIMETHYL-4A,4B,5,6,6A,6B,9A,10,10A,10B,11,12-DODECAHYDRO-9-OXA-7-AZA-PENTALENO[2,1-A]PHENANTHREN-2-ONE; Deflazacort Desacetoxy; (11b,16b)-11-hydroxy-2'-Methyl-5'-H-pregna-1,4-dieno 17,16 oxazole-3,20-dione; DEFLAZACORT INTERMEDIATE; 8b-Acetyl-7-hydroxy-6a,8a,10-trimethyl-6a,6b,7,8,8a,8b,11a,12,12a,12b-decahydro-1H-naphtho[2',1':4,5]indeno[1,2-d]oxazol-4(2H); (11β,16β)-11β-hydroxy-2'-Methyl-5βH-Pregna-1,4-dieno[17,16-d]oxazole-3,20-dione; 11β-hydroxy-2'-methyl-(16β)-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione; 21-DeacetoxyDeflazacor; (11B,16B)-11-HYDROXY-2-METHYL -5H-PREGNA-1,4-DIENO (17,16D)OXAZOLE-3,20-DIONE[D5]; Deflazacort Desacetoxy Impurity; Deflazacort Impurity 20; 11beta-Hydroxy-2'-methyl-5'betaH-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione; PREGNA-1,4-DIENE-11B-OL-17A,16A-D-2-METHYL-OXAZOLINE-3,20-DIONE; 11b-hydroxy-2-methyl-5b-H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione; 11BETA-HYDROXY-2'-METHYL-PREGNA-1,4-DIENE[17,16-D]OXAZOLE -__PROTECTED__3,20-DIONE; Intermediate of Difu Ke Te; Deflazacort Impurity 3; (11B,16b)-11-hydroxy-2’-methyl-5’-h-pregna-1,4-dieno[17,16]oxazole-3,20-dione; (11B, 16B)-11-HYDROXY-2'-METHYL-5'H-PREGNA-1,4-DIENO[17,16-D]OXAZOLE-3,20-DIONE; 5'H-Pregna-1,4-dieno[17,16-d]oxazole-3,20-dione, 11-hydroxy-2'-methyl-, (11β,16β); 1,4-Pregnadiene-11beta-ol-3,20-dione-[17alpha,16alpha-d]-2'-met; (4aR,4bS,5S,6aS,6bS,9aR,10aS,10bS)-6b-Acetyl-5-hydroxy-4a,6a,8-trimethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]oxazol-2-one

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 544.2±50.0 °C at 760 mmHg
• 熔点: >250°C (dec.)
• 分子式: C₂₃H₂₉NO₄
• 分子量: 383.481
• 闪点: 282.9±30.1 °C
• 精确质量: 383.209656
• PSA: 75.96000
• LogP: 1.06
• 蒸汽压: 0.0±3.3 mmHg at 25°C
• 折射率: 1.675
• 储存条件: Refrigerator

安全

• 海关编码: 2937290090

合成路线

13649-86-0 ~% 13649-88-2

文献：Steroids, , vol. 13, p. 383 - 397

13649-85-9 ~% 13649-88-2

文献：Journal of medicinal chemistry, , vol. 10, # 5 p. 799 - 802

16119-50-9 ~% 13649-88-2

文献：Journal of medicinal chemistry, , vol. 10, # 5 p. 799 - 802

19890-69-8 ~% 13649-88-2

文献：Steroids, , vol. 13, p. 383 - 397

13649-87-1 ~% 13649-88-2

文献：Steroids, , vol. 13, p. 383 - 397

19890-68-7 ~% 13649-88-2

文献：Steroids, , vol. 13, p. 383 - 397

14927-19-6 ~% 13649-88-2

文献：Journal of medicinal chemistry, , vol. 10, # 5 p. 799 - 802

19864-81-4 ~% 13649-88-2

文献：Steroids, , vol. 13, p. 383 - 397

22222-77-1 ~% 13649-88-2

文献：Steroids, , vol. 13, p. 383 - 397

上下游产品

上游产品  2
16119-50-9 13649-87-1
下游产品  1
14484-47-0

海关

海关编码	2937290090